Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda +9 more
wiley +1 more source
Natural Products Targeting Airway Inflammation and Mucus Hypersecretion: Molecular Mechanisms and Therapeutic Potential for Respiratory Health. [PDF]
Lee SG, Lee JH, Kang H.
europepmc +1 more source
This study quantitatively analyzed the spatiotemporal evolution of stress redistribution ahead of the working face by integrating coal seam distribution, tectonic stress anomalies, gas pressure, and mining‐induced disturbances. An R‐value criterion for coal and gas outburst (CGO) risk assessment was established based on energy principles.
Yingjie Zhao +7 more
wiley +1 more source
Toward a Cytological Classification of Nasal Biofilms in Upper Airway Inflammation: Microscopic Patterns, Clinical Meaning, and Therapeutic Implications. [PDF]
Gelardi M.
europepmc +1 more source
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane +4 more
wiley +1 more source
Nasal Cytology as a Local Biomarker of Airway Inflammation: A Paradigm Shift in Precision Medicine. [PDF]
Gelardi M.
europepmc +1 more source
Bronchial Fibroblasts Respond to IL-4 Challenge With Cytokine Secretion: Role in Allergic Airway Inflammation. [PDF]
Zhang D +7 more
europepmc +1 more source
Biomarkers of lung congestion and injury in acute heart failure
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi +9 more
wiley +1 more source
Author Correction: Platelet-derived serotonin epigenetically programs macrophage alternative activation to orchestrate type 2 airway inflammation. [PDF]
Tang R +17 more
europepmc +1 more source
Abstract Objective This study was undertaken to identify the incidence of respiratory tract infections (RTIs) in a large cohort of adult patients with status epilepticus (SE) and to characterize their associations with clinical features and outcome determinants.
Sebastian Berger +8 more
wiley +1 more source

