Results 1 to 10 of about 168 (162)
Management of airway obstruction [PDF]
Key points • Patients with airway obstruction are high risk; they should be managed by senior anaesthetic and surgical staffs that have good technical and non-technical skills. • There is no universal ‘best approach’ with experts often providing differing opinions on optimal management.
Lynch, J., Crawley, S. M.
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AIRWAY OBSTRUCTION IN CHILDREN [PDF]
Seventeen children presenting with airway obstruction have been studied to highlight the similar clinical features of different etiological conditions, their diagnostic limitations, and the importance of early bronchoscopy. There were 8 patients with foreign body in lower airway, out of which 6 were vegetable foreign bodies.
Dal Jit Singh+3 more
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Upper airways obstruction [PDF]
The tongue falling backwards and blocking the nasopharynx is the commonest cause of upper airway obstruction. However, it may be due to blood, vomit, oedema, or trauma. The mouth should be inspected and any foreign material removed manually or by suction. There are three manoeuvres to improve upper airway obstruction. 1. Head tilt.
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DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman+6 more
wiley +1 more source
A multifunctional memristor is demonstrated for in‐memory sensing and computing, leveraging a MoWS₂/VOx heterojunction to enable high ON/OFF ratio up to 10⁸ with ultralow operating voltages of ±0.2 V. This bio‐inspired multimodal design exhibits tunable synaptic behavior across electrical, optical, and humidity stimuli, enabling in situ modulation of ...
Abdul Momin Syed+8 more
wiley +1 more source
3D Printed Magnetic Origami Scaffolds for Guided Tissue Assembly
3D‐printed magnetic origami scaffolds enhance 3D coculture by directing cell proliferation pre‐folding, restricting expansion for controlled growth within the channel, and spatially and temporally promoting 3D multicellular dissemination post‐folding.
Brandon Daul+6 more
wiley +1 more source
4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea
A bilayer self‐folding scaffold, triggerable by humidity, is fabricated via 4D bioprinting for trachea engineering. An analytical model is derived to predict its radius of curvature, enabling its scalability. Cartilage progenitor cells seeded on the scaffold perceive scaffold final curvature and react to it, by enhancing the upregulation of pro ...
Irene Chiesa+4 more
wiley +1 more source
Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao+14 more
wiley +1 more source
AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu+8 more
wiley +1 more source
Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang+5 more
wiley +1 more source