Results 31 to 40 of about 170,918 (359)

Lung function in Lolland‐Falster Health Study (LOFUS)

The Clinical Respiratory Journal, 2022
Background COPD prevalence in Denmark is estimated at 18% based on data from urban populations. However, studies suggest that using the clinical cut‐off for airway obstruction in population studies may overestimate prevalence.
Katja Kemp Jacobsen, Randi Jepsen, Uffe Bodtger, Knud Rasmussen, Gry St‐Martin   +4 more
doaj   +1 more source

Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]

, 2019
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A., Buscemi R., Karch S. B., Lanzarone A., Roccuzzo R., Zerbo S.   +5 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Negative pressure pulmonary oedema following use of ProSeal LMA

Indian Journal of Anaesthesia, 2013
Negative pressure pulmonary oedema (NPPO) is a life threatening condition, manifested due to upper airway obstruction in a spontaneously breathing patient. Upper airway obstruction caused by classic laryngeal mask airway (cLMA) and ProSeal laryngeal mask
Richa Jain, Mahendra Kumar, Zainab A Haq, Ashim Banerjee   +3 more
doaj   +1 more source

New Spirometry Indices for Detecting Mild Airflow Obstruction. [PDF]

, 2018
The diagnosis of chronic obstructive pulmonary disease (COPD) relies on demonstration of airflow obstruction. Traditional spirometric indices miss a number of subjects with respiratory symptoms or structural lung disease on imaging.
Barjaktarevic, Igor, Bhakta, Nirav R, Bhatt, Surya P, Bodduluri, Sandeep, Castaldi, Peter J, Cooper, Christopher B, Dransfield, Mark T, Eberlein, Michael, Han, MeiLan K, Kim, Young-Il, Nakhmani, Arie, Sciurba, Frank C, Wilson, Carla G, Woodruff, Prescott G   +13 more
core   +2 more sources

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Challenges in diagnosis and management of central airway obstruction: Case series

SAGE Open Medical Case Reports
Central airway obstruction often presents with respiratory symptoms identical to those of common respiratory diseases. Diagnosis of central airway obstruction is challenging in clinical practice, especially misdiagnosed as asthma or chronic obstructive ...
Bao Le-Khac, Khoa Nguyen-Dang, Nam Vu-Hoai, Nam Nguyen-Thanh, Ngoc Duong-Minh, Thai-Hoa Tran-Ngoc, Lam Nguyen-Ho   +6 more
doaj   +1 more source

Predictors of tonsillectomy after previous adenoidectomy for upper airway obstruction [abstract] [PDF]

, 2010
One of the main indications for adenotonsillectomy in children is upper airway obstruction, including obstructive sleep apnea. Previous research has suggested an increased risk for requiring subsequent tonsillectomy when adenoidectomy alone is performed ...
Basler, Keith J., Mills, Jonathan C.
core  

Lung volumes identify an at-risk group in persons with prolonged secondhand tobacco smoke exposure but without overt airflow obstruction. [PDF]

, 2018
IntroductionExposure to secondhand smoke (SHS) is associated with occult obstructive lung disease as evident by abnormal airflow indices representing small airway disease despite having preserved spirometry (normal forced expiratory volume in 1 s-to ...
Arjomandi, Mehrdad, Blanc, Paul D, Bos, Bruce, Elicker, Brett, Geerts, Jeroen, Gold, Warren M, Keene, Jason, Stiner, Rachel K, van Koeverden, Ian, Zeng, Siyang   +9 more
core   +2 more sources