Results 111 to 120 of about 18,946 (199)

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone   +1 more
wiley   +1 more source

Breathing irregularities and postnatal hypoxaemia in an experimental model of essential hypertension

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Neonatal spontaneously hypertensive rats (SHRs) exhibit inherent respiratory dysfunction in early life, including oscillatory breathing patterns and apnoeic events that cause oxygen desaturation and brain hypoxia, in addition to an impaired hypoxic ventilatory response.
Beatriz N. Vieira   +7 more
wiley   +1 more source

SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu   +5 more
wiley   +1 more source

Prenatal air pollution exposure is associated with altered neurodevelopmental outcomes in early childhood

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study examined the effect of modelled maternal air pollution exposure during gestation on neurodevelopment in a community cohort of 498 toddlers recruited from Greater London, UK. Higher 1st trimester exposure to particulate matter and nitrogen dioxide was associated with lower language scores at 18 months adjusting for ...
Alexandra F. Bonthrone   +11 more
wiley   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise   +2 more
wiley   +1 more source

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