Results 31 to 40 of about 240,500 (234)

Airway remodelling and its relationship to inflammation in cystic fibrosis

open access: yes, 2010
Pulmonary disease is the most important cause of morbidity and mortality in cystic fibrosis (CF). Most patients with CF die from respiratory failure with extensive airway destruction.
Davies, Jane C   +14 more
core   +1 more source

RhoA/Rho‐kinases in asthma: from pathogenesis to therapeutic targets

open access: yesClinical & Translational Immunology, 2020
Asthma is a chronic and heterogeneous disease characterised by airway inflammation and intermittent airway narrowing. The key obstacle in the prevention and treatment of asthma has been our incomplete understanding of its aetiology and biological ...
Yan Zhang   +7 more
doaj   +1 more source

Cholinergic regulation of airway inflammation and remodelling [PDF]

open access: yes, 2012
Acetylcholine is the predominant parasympathetic neurotransmitter in the airways that regulates bronchoconstriction and mucus secretion. Recent findings suggest that acetylcholine regulates additional functions in the airways, including inflammation and ...
Gosens, Reinoud, Kolahian, Saeed
core   +1 more source

Airway Remodelling in Response to Novel Asthma Therapies

open access: yes, 2020
Airway remodelling encompasses a range of structural changes seen in the airways of asthma patients, and can be assessed in bronchial biopsy samples. However, there is a paucity of data investigating remodelling responses to asthma therapies.
Richard Russell (385829)
core   +1 more source

Airway wall remodeling in asthma : novel mechanisms of human bronchial smooth muscle cells in the induction of angiogenesis [PDF]

open access: yes, 2014
Asthma is a global major health concern and it affects estimated 300 million people. The prevalence of asthma is rising and there is no cure for asthma, only the symptoms can be controlled.
Keglowich, Laura Franziska
core   +1 more source

The role of the bronchial microvasculature in the airway remodelling in asthma and COPD

open access: yesRespiratory Research, 2010
In recent years, there has been increased interest in the vascular component of airway remodelling in chronic bronchial inflammation, such as asthma and COPD, and in its role in the progression of disease.
Spanevello Antonio   +4 more
doaj   +1 more source

Airway remodelling and inflammation features in bronchial biopsies.

open access: yes, 2016
Airway remodelling and inflammation features in bronchial biopsies.
Camille Taillé (829699)   +8 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Advanced Flexible Robotic Systems for the Early Diagnosis and Treatment of Cancer and Cardiovascular Diseases

open access: yesAdvanced Robotics Research, EarlyView.
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong   +14 more
wiley   +1 more source

More airway smooth muscle in males versus females in a mouse model of asthma: A blessing in disguise?

open access: yesExperimental Physiology, 2023
Mouse models are helpful in unveiling the mechanisms underlying sex disparities in asthma. In comparison to their female counterparts, male mice are hyperresponsive to inhaled methacholine, a cardinal feature of asthma that contributes to its symptoms ...
Rebecka Gill   +4 more
doaj   +1 more source

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