Scientific Reports, 2023 Allergic asthma is associated with chronic airway inflammation and progressive airway remodelling. The sclerotium of Lignosus rhinocerotis (Cooke) Ryvarden (Tiger Milk mushroom) is used traditionally to treat various illnesses, including asthma in ...
Siti-Aminah Muhamad +5 more
doaj +1 more source
Independent and combined effects of airway remodelling and allergy on airway responsiveness
, 2018 Airway remodelling and allergic inflammation are key features of airway hyperresponsiveness (AHR) in asthma; however, their interrelationships are unclear. The present study investigated the separate and combined effects of increased airway smooth muscle
James, AL (15503057) +6 more
core +3 more sources
Can HRCT be used as a marker of airway remodelling in children with difficult asthma? [PDF]
, 2006 BACKGROUND: Whole airway wall thickening on high resolution computed tomography (HRCT) is reported to parallel thickening of the bronchial epithelial reticular basement membrane (RBM) in adult asthmatics. A similar relationship in children with difficult
Khoo L +18 more
core +1 more source
Airway Smooth Muscle Remodelling in Mild and Moderate Equine Asthma
, 2021 Excel file containing data related to the manuscript Airway Smooth Muscle Remodelling in Mild and Moderate Equine ...
Dupuis-Dowd, Florence
core +1 more source
Bronchial smooth muscle cell in asthma: where does it fit?
BMJ Open Respiratory Research, 2022 Asthma is a frequent respiratory condition whose pathophysiology relies on altered interactions between bronchial epithelium, smooth muscle cells (SMC) and immune responses.
Gervaise Loirand +5 more
doaj +1 more source
Fluticasone/salmeterol reduces remodelling and neutrophilic inflammation in severe equine asthma
Scientific Reports, 2017 Asthmatic airways are inflamed and undergo remodelling. Inhaled corticosteroids and long-acting β2-agonist combinations are more effective than inhaled corticosteroid monotherapy in controlling disease exacerbations, but their effect on airway ...
Michela Bullone +4 more
doaj +1 more source
Regulation of human airway smooth muscle cell migration and relevance to asthma
Respiratory Research, 2017 Airway remodelling is an important feature of asthma pathogenesis. A key structural change inherent in airway remodelling is increased airway smooth muscle mass.
Brittany Salter +4 more
doaj +1 more source
Tgf-Beta isoform specific regulation of airway inflammation and remodelling in a murine model of asthma. [PDF]
PLoS ONE, 2010 The TGF-beta family of mediators are thought to play important roles in the regulation of inflammation and airway remodelling in asthma. All three mammalian isoforms of TGF-beta, TGF-beta(1-3), are expressed in the airways and TGF-beta(1) and -beta(2 ...
Stephen E Bottoms +4 more
doaj +1 more source
Mechanisms of airway epithelial injury and abnormal repair in asthma and COPD
Frontiers in Immunology, 2023 The airway epithelium comprises of different cell types and acts as a physical barrier preventing pathogens, including inhaled particles and microbes, from entering the lungs.
Katie Louise Raby +7 more
doaj +1 more source
Inflammation-dependent and independent airway remodelling in asthma [PDF]
, 2018 Background and objective: The pathology of asthma is characterized by airway inflammation (granulocytic (GA) or paucigranulocytic (PGA)) and remodelling of airway structures.
McKay, Karen O. +7 more
core +1 more source