Results 11 to 20 of about 3,252,729 (140)

Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia

open access: yesScience Translational Medicine, 2019
A next-generation, broad-spectrum, orally efficacious influenza A and B virus inhibitor is associated with a high genetic resistance barrier. Treating flu, escaping resistance Influenza viruses can cause severe illness and death.
M. Toots   +16 more
semanticscholar   +1 more source

On the Advantages of Specific Airway Resistance [PDF]

open access: yesPediatric Research, 1978
The specific airway resistance (SRaw) is a relatively precise parameter of bronchial quality and in normal children its relation with body length, although very significant (P less than 0.001), is so poor that it can safely be disregarded (Fig. 4). Also the dispersion around the mean value remains stable at any body size (Fig. 4).
I Dab, F Alexander
openaire   +3 more sources

Polymicrobial Interactions in the Cystic Fibrosis Airway Microbiome Impact the Antimicrobial Susceptibility of Pseudomonas aeruginosa

open access: yesAntibiotics, 2021
Pseudomonas aeruginosa is one of the most dominant pathogens in cystic fibrosis (CF) airway disease and contributes to significant inflammation, airway damage, and poorer disease outcomes.
E. Reece, P. H. Bettio, J. Renwick
semanticscholar   +1 more source

Nonlinearity of intratidal airway resistance [PDF]

open access: yesCritical Care, 2007
Acute respiratory distress syndrome is a disease associated with high mortality. Understanding the interdependence of ventilator settings and respiratory mechanics is crucial for further developments of protective lung ventilation. Up to now, the nonlinearity of compliance has mainly been the focus of interest.
H Knorpp   +4 more
openaire   +2 more sources

Airways resistance and specific conductance for the diagnosis of obstructive airways diseases [PDF]

open access: yesRespiratory Research, 2015
Airway resistance (RAW) and specific airway conductance (sGAW) are measures that reflect the patency of airways. Little is known of the variability of these measures between different lung diseases. This study investigated the contribution of RAW and sGAW to a diagnosis of obstructive airways disease and their role in differentiating asthma from COPD ...
Topalovic, Marko   +16 more
openaire   +4 more sources

Long-term Exposure to PM10 and NO2 in Association with Lung Volume and Airway Resistance in the MAAS Birth Cohort

open access: yesEnvironmental Health Perspectives, 2013
Background: Findings from previous studies on the effects of air pollution exposure on lung function during childhood have been inconsistent. A common limitation has been the quality of exposure data used, and few studies have modeled exposure ...
Anna Mölter   +8 more
semanticscholar   +1 more source

Airway resistance at maximum inhalation as a marker of asthma and airway hyperresponsiveness [PDF]

open access: yesRespiratory Research, 2011
Abstract Background Asthmatics exhibit reduced airway dilation at maximal inspiration, likely due to structural differences in airway walls and/or functional differences in airway smooth muscle, factors that may also increase airway responsiveness to bronchoconstricting stimuli.
Jennifer Kenyon   +5 more
openaire   +4 more sources

THE EFFECT OF PROPRANOLOL ON AIRWAY RESISTANCE

open access: yesBritish Journal of Anaesthesia, 1967
The effect of propranolol on the airway resistance (AWR) of eighteen normal and seven asthmatic subjects has been studied by whole body plethysmography. In normal subjects there was a significant mean rise in AWR which was never accompanied by any respiratory upset.
Charles G. Ingram   +2 more
openaire   +3 more sources

The effect of inhaled menthol on upper airway resistance in humans: a randomized controlled crossover study.

open access: yesCanadian Respiratory Journal, 2013
BACKGROUND Menthol (l-menthol) is a naturally-occurring cold receptor agonist commonly used to provide symptomatic relief for upper airway congestion. Menthol can also reduce the sensation of dyspnea.
E. Pereira   +4 more
semanticscholar   +1 more source

A cause of excessive daytime sleepiness. The upper airway resistance syndrome.

open access: yesChest, 1993
Subjects with isolated complaints of chronic daytime sleepiness are usually classified as "idiopathic hypersomniacs" and treated symptomatically. A group of these subjects was investigated during nocturnal sleep and daytime naps.
C. Guilleminault   +4 more
semanticscholar   +1 more source

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