The Mechanism of Drug-induced Akathisia [PDF]
Akathisia is a movement disorder character-ized by an inner sense of unease, unrest, and dys-phoria. It can result in an inability to stand, sit, orlie still, and an intense urge to move around. It isa common side effect of drugs, such as antipsy-chotics
Loonen, Anton J. M. +2 more
core +3 more sources
Brainstem reflexes are hyperactive in patients with drug-induced akathisia
Akathisia is a sensori-motor phenomenon which is generally encountered as an adverse effect of antidopaminergic medications suggesting involvement of dopaminergic pathways. We recently showed nociceptive flexor reflex was altered in akathisia as compared
Gunes Kiziltan +14 more
core +4 more sources
Different types of akathisia: clinical analysis on three cases
Objective To explore the clinical presentations, probable pathogenesis and therapy of different types of akathisia. Methods and Results There were 3 cases of akathisia in this report. The diagnosis of Case 1 was acute akathisia, drug-induced parkinsonism,
Lei WANG +4 more
doaj +2 more sources
Drug-induced akathisia as a cause of distress in spouse caregivers of cancer patients
Objective:Family caregivers of cancer patients suffer from physical, psychological, and social distress and therefore are often referred to as second order patients.
Yumi Iwamitsu +10 more
core +3 more sources
Objective: The study aims to determine if slow intravenous infusion of metoclopramide reduces the incidence of acute drug-induced akathisia (DIA) compared with intravenous bolus.
K. Povey (23348707) +1 more
core +5 more sources
Epilepsy-Related Psychosis in Drug-Resistant Epilepsy With Nonconvulsive Status Epilepticus and Difficult Antipsychotic Titration: A Case Report. [PDF]
Electroclinical findings supported diazepam‐responsive nonconvulsive status epilepticus (NCSE) in an older patient with drug‐resistant epilepsy and psychosis. After phenytoin treatment, continuous EEG helped monitor recurrence. Later symptoms were most consistent with interictal psychosis with a possible alternative psychosis component, emphasizing ...
Omori W +4 more
europepmc +2 more sources
Psychometric Properties of Instruments to Assess Movement Disorders in People With Intellectual Disabilities Using Antipsychotics: A Systematic Literature Review. [PDF]
ABSTRACT Background Assessing movement disorders—side effects of antipsychotics—can be challenging in people with intellectual disabilities. This systematic literature review aims to provide a comprehensive overview of the psychometric properties of instruments used to assess movement disorders in people with intellectual disabilities using ...
Hoekstra-van Duijn MLD +4 more
europepmc +2 more sources
Akathisia Induced by Metoclopramide in a Pregnant Woman With Nausea and Vomiting: A Case Report. [PDF]
This case report describes a patient who was hospitalized at 33 weeks of gestation and diagnosed with metoclopramide‐induced akathisia. Although the akathisia symptoms resolved 3 days after discontinuation of metoclopramide, a possible interaction with dextromethorphan, which the patient had been orally administering prior to hospitalization, cannot be
Nakamura R +6 more
europepmc +2 more sources
Comparative Efficacy and Acceptability of Treatment Strategies for Antipsychotic-Induced Akathisia: A Systematic Review and Network Meta-analysis. [PDF]
BACKGROUND Antipsychotics are the treatment of choice for schizophrenia, but they often induce akathisia. However, comparative efficacy of treatment strategies for akathisia remains unclear.
Furukawa Y +4 more
europepmc +3 more sources
Tardive Dyskinesia in Patients Receiving Continuous Versus Intermittent Oral Metoclopramide: A Retrospective Real World Study. [PDF]
Continuous MCP dosing was associated with higher TD prevalence and earlier onset. Intermittent dosing, despite longer cumulative exposure, was associated with lower TD risk. These findings suggest that intermittent regimens may offer a safer MCP therapeutic strategy. ABSTRACT Background Tardive dyskinesia (TD) is an often irreversible movement disorder
Russo P, Nathan R, Camilleri M.
europepmc +2 more sources

