Results 91 to 100 of about 513 (121)

IRES-like element-mediated translation of vsp1S4(-) suppresses BmCPV replication via RNAi antagonism. [PDF]

open access: yesPLoS Pathog
Chen X   +8 more
europepmc   +1 more source
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Identification and primary immune characteristics of an amphioxus akirin homolog

Fish & Shellfish Immunology, 2013
Akirin is a recently described nuclear protein that is thought to be required for the NF-κB signaling pathway in insects and vertebrates. Here, functional investigations of akirin are described in the basal chordate amphioxus Branchiostoma belcheri tsingtauense in an attempt to link this gene between insect and vertebrate lineages.
Jie, Yan   +5 more
openaire   +4 more sources

Molecular characterization and functional analysis of Akirin from black tiger shrimp (Penaeus monodon)

Fish & Shellfish Immunology, 2019
Akirin, which are members of the NF-κB signaling pathway, play critical roles in regulating the expression of antimicrobial peptides. In the present study, the Akirin gene from Penaeus monodon was identified from a transcriptome database and designated as PmAkirin.
Chao, Peng   +7 more
openaire   +4 more sources

Targeting arthropod subolesin/akirin for the development of a universal vaccine for control of vector infestations and pathogen transmission

Veterinary Parasitology, 2011
Diseases caused by arthropod-borne pathogens greatly impact on human and animal health. Recent research has provided evidence that tick protective antigens can be used for development of vaccines with the dual target of controlling arthropod infestations and reducing their vector capacity for pathogens.
Fuente, José de la   +8 more
openaire   +5 more sources

Akirins versus infection

Nature Immunology, 2008
Over 20 years have passed since the discovery of NF-κB and its signaling pathways, yet additional participants continue to be identified. The highly conserved protein Akirin is such an example.
Bruce Beutler, Eva Marie Y Moresco
openaire   +1 more source

The identification of nuclear factor Akirin with immune defense role in silkworm, Bombyx mori

International Journal of Biological Macromolecules, 2021
Akirins, highly conserved nuclear factors, regulate diverse physiological processes such as innate immunity. The biological functions of Akirins have extensively been studied in vertebrates and many invertebrates; however, there is no report so far on lepidopteran insects.
Xin, Hu   +10 more
openaire   +2 more sources

Alkaloids of Aconitum kirinense. Structure of akirine

Chemistry of Natural Compounds, 1992
The known alkaloid lepenine and the new diterpene alkaloid akirine have been isolated from the epigeal part ofAconitum kirinense Nakai. To establish the structure of akirine, its spectral characteristics have been studied and an x-ray structural analysis has been made. It is 1α,8β-dihydroxy-16β-methoxy-9β,14β-methylenedioxy-3β,4β-epoxy-N-ethylaconitane
A. A. Nishanov   +3 more
openaire   +1 more source

Akirins in sea lice: First steps towards a deeper understanding

Experimental Parasitology, 2013
Sea lice (Copepoda, Caligidae) are the most widely distributed marine pathogens in the salmon industry. Vaccination could be an environmentally friendly alternative for sea lice control; however, research on the development of such vaccines is still at an early stage of development.
Yamila, Carpio   +7 more
openaire   +2 more sources

Control of multiple arthropod vector infestations with subolesin/akirin vaccines

Vaccine, 2013
Diseases transmitted by arthropod vectors such as mosquitoes, ticks and sand flies greatly impact human and animal health and thus their control is important for the eradication of vector-borne diseases (VBD). Vaccination is an environmentally friendly alternative for vector control that allows control of several VBD by targeting their common vector ...
Juan A, Moreno-Cid   +9 more
openaire   +2 more sources

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