Phospho-Akt expression is high in a subset of triple negative breast cancer patients [PDF]
, 2014 The most commonly used biomarkers to predict the response of breast cancer patients to therapy are oestrogen receptor (ER), progesterone receptor (PgR), and human epidermal growth factor receptor 2 (HER2).
Baldacchino, Shawn +6 more
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Akt regulates skeletal development through GSK3, mTOR, and FoxOs [PDF]
, 2009 Although Akt plays key roles in various cellular processes, the functions of Akt and Akt downstream signaling pathways in the cellular processes of skeletal development remain to be clarified. By analyzing transgenic embryos that expressed constitutively
Liu, Wenguang +7 more
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adaptive capabilities of the pi3k/akt/mtor pathway in acute myeloid leukemia revealed by the use of selective inhibitors [PDF]
, 2013 Because of its aberrant activation, the PI3K/AKT/mTOR signaling pathway represents a pharmacological target in blast cells from patients with acute myelogenous leukemia (AML).
Bertacchini, Jessika <1980>
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Activation of Akt at T308 and S473 in alcohol, tobacco and HPV-induced HNSCC:is there evidence to support a prognostic or diagnostic role? [PDF]
, 2014 BACKGROUND: Tobacco, alcohol and HPV infection are associated with increased risk of HNSCC. However, little is known about the underlying signaling events influencing risk.
Ellis, Ian R.; id_orcid +9 more
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Oligonucleotides suppress PKB/Akt and act as superinductors of apoptosis in human keratinocytes [PDF]
, 2009 DNA oligonucleotides (ODN) applied to an organism are known to modulate the innate and adaptive immune system. Previous studies showed that a CpG-containing ODN (CpG-1-PTO) and interestingly, also a non-CpG-containing ODN (nCpG- 5-PTO) suppress ...
Annette Dorn +19 more
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Towards an understanding of protein kinase B (PKB/Akt) function in mouse development [PDF]
, 2004 Protein kinase B (PKB/Akt) belongs to a subfamily of serine/threonine protein kniases called AGC protein kinases. Homologues of PKB can be found in worms, flies and mammals.
Yang, Zhong-Zhou
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An innovative digital workflow to design, build and manage bamboo structures
Sustainable Structures, 2022 At current rates, the building industry is the major contributor to gas emissions and energy consumption in the world, placing unprecedented pressure to find alternative and sustainable construction materials, particularly in regions where urbanization ...
Leonel Mimendi +2 more
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A jednak dokument papierowy, czyli spojrzenie archiwisty – tradycjonalisty
Archiwa - Kancelarie - Zbiory, 2015 W kancelariach, archiwach historycznych i bieżących coraz powszechniej stosowane są usprawniające pracę urządzenia techniczne oraz komputery zaopatrzone w wyspecjalizowane oprogramowanie.
Adam Grzegorz Dąbrowski
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Animal Cells and Systems, 2021 Endometrial cancer is the most common gynecological cancer in the developed countries. Type II transmembrane serine proteases 4 (TMPRSS4) is a newly discovered transmembrane protein, which may be related to the invasion, metastasis of the tumor and the ...
Huan Xiao +4 more
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Frontiers in Pharmacology, 2021 The Yi–Qi–Jian–Pi–Xiao–Yu–Xie–Zhuo (YQJPXYXZ) formula has been used for treating chronic kidney disease (CKD) for many years with good efficiency based on the cumulative empirical experience of previous practitioners.
Hong Xia +11 more
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