Results 11 to 20 of about 435,283 (261)

Yi–Qi–Jian–Pi–Xiao–Yu–Xie–Zhuo Formula Improves Muscle Atrophy via Modulating the IGF-1/PI3K/Akt Signaling Pathway in 5/6 Nephrectomized Rats

open access: yesFrontiers in Pharmacology, 2021
The Yi–Qi–Jian–Pi–Xiao–Yu–Xie–Zhuo (YQJPXYXZ) formula has been used for treating chronic kidney disease (CKD) for many years with good efficiency based on the cumulative empirical experience of previous practitioners.
Hong Xia   +11 more
doaj   +1 more source

Current Perspectives on Akt Akt-ivation and Akt-ions

open access: yesExperimental Biology and Medicine, 2009
The serine/threonine kinase Akt is an effector of PI3K-generated phosphatidylinositol ( 3 , 4 , 5 )-trisphosphate [PI( 3 , 4 , 5 )P3] and is a principle mediator of growth factor-induced signal transduction. Akt is activated through phosphorylation by specific kinases, and its activity is reduced directly by phosphorylation-site-specific phosphatases ...
Ronald W, Matheny, Martin L, Adamo
openaire   +2 more sources

Aspek Kepemimpinan Manajemen, Praktik Manajemen Mutu Terpadu, dan Quality Performance: Analisa PLS-Path Modeling

open access: yesJurnal Dinamika Akuntansi dan Bisnis, 2019
This study aims to predict the causal relationships between management leadership, total quality management practices, and quality performance. Data is collected from a survey through the distribution of questionnaires.
Kurniawan Tjakrawala, Nurainun Bangun
doaj   +1 more source

Inhibitory Effect of Hesperidin on the Expression of Programmed Death Ligand (PD-L1) in Breast Cancer

open access: yesMolecules, 2020
Programmed death ligand 1 (PD-L1) is overexpressed in the most aggressive breast cancer subtype, triple-negative breast cancer (TNBC), assisting the eradication of antitumor immunity, and thereby enhancing the survival of the tumor.
Prachya Kongtawelert   +4 more
doaj   +1 more source

Analysis of expression pattern of proteins associated with AKT/mTOR signaling pathway in kidney cancer development

open access: yesAnnals of Medical Science and Research, 2022
Introduction: The purpose of this study was to analyze the expression status, reciprocal interplay, and prognostic significance of AKT1 and hypoxia-inducible factor 1 alpha (HIF-1α) in AKT/mechanistic target of the rapamycin pathway and to enable them to
Ritesh Satardey   +3 more
doaj   +1 more source

PERBANDINGAN EARLY WARNING SYSTEMS (EWS) UNTUK MEMPREDIKSI KEBANGKRUTAN BANK UMUM DI INDONESIA

open access: yesBuletin Ekonomi Moneter dan Perbankan, 2005
This research is testing the capability of several forewarning system models to predict bank bankruptcy. We apply these models on Indonesian commercial bank data during the period of 1994/ 1995 - 1999/2000.
Liza Angelina, SE, Msi, Akt
doaj   +1 more source

Developing associative models to guide typological strategies for better integrating Waste to Energy plants in an urban context

open access: yesRi-vista: Ricerche per la Progettazione del Paesaggio, 2018
Despite many advantages may be oered including architectural expertise in the design and delivery of industrial buildings and power plants, in recent times it has generally been excluded from this process, probably because of the lack of cleoles for ...
Hanif Kara   +2 more
doaj   +1 more source

Protective effects of 3-n-butylphthalide on cerebral infarction induced by local ischemic injury and regulation mechanism of the pi3k/akt/gsk- 3β signaling pathway [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2023
We aimed to study the protective effects of 3-n-butylphthalide (NBP) on cerebral infarction induced by local ischemic injury and regulation mechanism of the PI3K/Akt/GSK-3β signaling pathway.
Ke LI, Yan CAO, Jie ZHANG
doaj   +1 more source

Akt Inhibitor Akt-IV Blocks Virus Replication through an Akt-Independent Mechanism [PDF]

open access: yesJournal of Virology, 2009
ABSTRACTMany viruses activate the phosphatidylinositol 3′-kinase (PI3k)/Akt intracellular signaling pathway to promote viral replication. We have analyzed whether a rapidly replicating rhabdovirus, vesicular stomatitis virus (VSV), requires the PI3k/Akt signaling pathway for its replication.
Ewan F, Dunn   +2 more
openaire   +2 more sources

Crosstalk between PI3K/Akt and Wnt/β-catenin pathways promote colorectal cancer progression regardless of mutational status

open access: yesCancer Biology & Therapy, 2022
The PI3K/Akt and Wnt/β-catenin pathways play an important role in the acquisition of the malignant phenotype in cancer. However, there are few data regarding the role of the interplay between both pathways in colorectal cancer (CRC) progression.
Cassio Dejair Fleming-de-Moraes   +4 more
doaj   +1 more source

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