Results 41 to 50 of about 532,309 (312)
The Akt-associated microRNAs [PDF]
Cellular and Molecular Life Sciences, 2012 As master gene regulators, microRNAs are involved in diverse cellular pathways. It is well known that microRNAs are often dysregulated in many types of cancer and other human diseases. In cancer, microRNAs may function as oncogenes or tumor suppressors.
Min, Xu, Yin-Yuan, Mo
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PERBANDINGAN EARLY WARNING SYSTEMS (EWS) UNTUK MEMPREDIKSI KEBANGKRUTAN BANK UMUM DI INDONESIA
Buletin Ekonomi Moneter dan Perbankan, 2005 This research is testing the capability of several forewarning system models to predict bank bankruptcy. We apply these models on Indonesian commercial bank data during the period of 1994/ 1995 - 1999/2000.
Liza Angelina, SE, Msi, Akt
doaj +1 more source
Metastasis and AKT activation [PDF]
Journal of Cellular Physiology, 2008 AbstractMetastasis, responsible for 90% of cancer patient deaths, is an inefficient process because many tumor cells die. The survival of metastatic tumor cells should be considered as a critical therapeutic target. This review provides a new perspective regarding the role of AKT in tumor survival, and the rationale to target AKT in anti‐metastasis ...
Meng, Qiao +2 more
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Ri-vista: Ricerche per la Progettazione del Paesaggio, 2018 Despite many advantages may be oered including architectural expertise in the design and delivery of industrial buildings and power plants, in recent times it has generally been excluded from this process, probably because of the lack of cleoles for ...
Hanif Kara +2 more
doaj +1 more source
, 2013 Because of its aberrant activation, the PI3K/AKT/mTOR signaling pathway represents a pharmacological target in blast cells from patients with acute myelogenous leukemia (AML).
Bertacchini, Jessika <1980>
core +1 more source
ErbB2 signaling in breast cancer : the role of ErbB, Akt and ShcA phosphorylation [PDF]
, 2004 Breast cancer is the most common malignancy in women and is estimated to account for more than 200,000 new cancer cases in the United States in the year 2002. It now represents the second leading cause of death (40,000) from cancer in women.
Cicenas, Jonas
core +1 more source
Phosphorylation of HDM2 by Akt [PDF]
Oncogene, 2002 The HDM2 protein is a key regulator of the tumour suppressor, p53. Control of HDM2 function is critical for normal cell proliferation and stress responses, and it is becoming evident that multiple modifications of HDM2 can regulate its function within cells.
Margaret, Ashcroft +6 more
openaire +2 more sources
mTOR complex 2 - akt signaling is physically and functionally at mam [PDF]
, 2012 The target of rapamycin (TOR) is a conserved protein kinase and a central controller of growth. TOR can be part of two structurally and functionally distinct complexes, termed TOR complex 1 and TOR complex 2.
Betz, Charles
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source