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O czym nie napisała Marta Zyn? Edycja dziennika kijowskiej nauczycielki z lat 1919–1922

Dzieje Najnowsze
Przedmiotem artykułu jest analiza Dziennika Marty Zyn (właśc. Marty Wołoszynowskiej) z lat 1919–1922, przygotowanego do druku przez Joannę Gierowską-Kałłaur i Martę Parnowską. Nie zachował się jego rękopiśmienny oryginał.
Henryk Bartoszewicz
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A Small Molecule Inhibits Akt through Direct Binding to Akt and Preventing Akt Membrane Translocation [PDF]

Journal of Biological Chemistry, 2010
The Akt pathway is frequently hyperactivated in human cancer and functions as a cardinal nodal point for transducing extracellular and intracellular oncogenic signals and, thus, presents an exciting target for molecular therapeutics. Here we report the identification of a small molecule Akt/protein kinase B inhibitor, API-1.
Donghwa, Kim, Mei, Sun, Lili, He, Qing-Hua, Zhou, Jun, Chen, Xia-Meng, Sun, Gerold, Bepler, Said M, Sebti, Jin Q, Cheng   +8 more
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AKT signaling mediates IGF-I survival actions on otic neural progenitors [PDF]

, 2012
Background: Otic neurons and sensory cells derive from common progenitors whose transition into mature cells requires the coordination of cell survival, proliferation and differentiation programmes.
Sanchez-Calderon, Hortensia, Marta Magariños, Leon, Yolanda, Maria R Aburto, Maria R. Aburto (186884), Varela-Nieto, Isabel, Yolanda Leon (5649538), Leon Yolanda, Yolanda Leon, Rodriguez Aburto, Maria, Magariños Marta, Hortensia Sanchez-Calderon, Hortensia Sanchez-Calderon (186893), Isabel Varela-Nieto (186892), Marta Magariños (186888), Aburto Maria R., Isabel Varela-Nieto, Varela-Nieto Isabel, Sanchez-Calderon Hortensia, Magariños, Marta   +19 more
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PI3K, AKT, and P-AKT levels in thin endometrium

Genetics and Molecular Research, 2016
The aim of this study was to explore the expression of PI3K, AKT, and P-AKT, and to investigate the role of PI3K/AKT signaling pathway in thin endometrium. We included 40 women treated in affiliated Shenzhen Nanshan People's Hospital of Guangdong Medical University for endometrial conditions between August 2013 and January 2015, 20 with a normal ...
A W, Le, L L, Shan, X Y, Dai, T H, Xiao, X R, Li, Z H, Wang, J, Zhang, X Y, Chen   +7 more
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Fos co-operation with PTEN loss elicits keratoacanthoma not carcinoma due to p53/p21^WAF-induced differentiation triggered by GSK3b inactivation and reduced AKT activity [PDF]

, 2008
To investigate gene synergism in multistage skin carcinogenesis, the RU486-inducible cre/lox system was employed to ablate PTEN function [K14.cre/D5PTENflx] in mouse epidermis expressing activated v-fos [HK1.fos].
Chan, W-C., Wu, H., Weng-Chyn Chan, Alexander, C.L., Yao, D., Claire L. Alexander, Jean A. Quinn, Hong Wu, David A. Greenhalgh, Greenhalgh, D.A., Quinn, J., Denggao Yao   +11 more
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Developing associative models to guide typological strategies for better integrating Waste to Energy plants in an urban context

Ri-vista: Ricerche per la Progettazione del Paesaggio, 2018
Despite many advantages may be oered including architectural expertise in the design and delivery of industrial buildings and power plants, in recent times it has generally been excluded from this process, probably because of the lack of cleoles for ...
Hanif Kara, Leire Asensio Villoria, Elisabet Höglund,   +2 more
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Akt destabilizes p57^Kip2: Akt at the converging crossroad? [PDF]

Cell Cycle, 2013
Cell cycle progression through the G1 phase is tightly controlled by cyclin-dependent kinases (CDKs). Activity of CDKs is negatively regulated by two unrelated families of CDK inhibitors (CDKi), namely, INK and Cip/Kip. The Cip/Kip family of CDKi consists of three members, p21Cip1/WAF1, p27Kip1 and p57Kip2.
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Crosstalk between PI3K/Akt and Wnt/β-catenin pathways promote colorectal cancer progression regardless of mutational status

Cancer Biology & Therapy, 2022
The PI3K/Akt and Wnt/β-catenin pathways play an important role in the acquisition of the malignant phenotype in cancer. However, there are few data regarding the role of the interplay between both pathways in colorectal cancer (CRC) progression.
Cassio Dejair Fleming-de-Moraes, Murilo Ramos Rocha, Josiane Weber Tessmann, Wallace Martins de Araujo, Jose Andres Morgado-Diaz   +4 more
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Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells [PDF]

, 2014
The insulin/IGF-1 (insulin-like growth factor 1)-activated protein kinase Akt (also known as protein kinase B) phosphorylates Ser487 in the ‘ST loop’ (serine/threonine-rich loop) within the C-terminal domain of AMPK-a1 (AMP-activated protein kinase-a1 ...
Leslie, Nicholas R., Leslie, Nicholas R.; id_orcid, Ross, Fiona A., Hardie, D. Grahame, Tibarewal, Priyanka, Gowans, Graeme J., Hawley, Simon A.   +6 more
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LncRNA DUXAP8 induces breast cancer radioresistance by modulating the PI3K/AKT/mTOR pathway and the EZH2-E-cadherin/RHOB pathway

Cancer Biology & Therapy, 2022
Radiation resistance poses a major clinical challenge in breast cancer (BC) treatment, but little is known about how long noncoding RNA (lncRNA) may regulate this phenomenon. Here, we reported that DUXAP8 was highly expressed in radioresistant BC tissues,
Changjiang Lei, Shaoting Li, Ying Fan, Li Hua, Qingyun Pan, Yuan Li, Zhixiong Long, Rui Yang   +7 more
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