Results 121 to 130 of about 109,106 (257)

Anti-fibrotic effects of Cuscuta chinensis with in vitro hepatic stellate cells and a thioacetamide-induced experimental rat model

Pharmaceutical Biology, 2017
Context: Cuscuta chinensis Lam. (Convolvulaceae) has been used as a traditional herbal remedy for treating liver and kidney disorders. Objective: Anti-fibrotic effects of C.
Jin Seoub Kim, Sushruta Koppula, Mun Jeong Yum, Gwang Mo Shin, Yun Jin Chae, Seok Min Hong, Jae Dong Lee, MinDong Song   +7 more
doaj   +1 more source

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

Advanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão, Susana Simões, Paulo Rodrigues‐Santos, Vitor Francisco, Akhilesh Rai, Lino Ferreira   +5 more
wiley   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Why Is the Mechanism Underlying the Chiral‐Induced Selectivity Effect Still Challenging?

Advanced Materials, EarlyView.
The chiral‐induced spin selectivity (CISS) effect is observed in many experimental configurations and for different materials. However, there are theoretical challenges in attempting to explain those results. A qualitative framework for explaining all the results is presented.
Ron Naaman, Yossi Paltiel
wiley   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Alanine Water Complexes

, 2016
Two complexes of alanine with water, alanine–(H2O)n (n = 1,2), have been generated by laser ablation of the amino acid in a supersonic jet containing water vapor and characterized using Fourier transform microwave spectroscopy. In the observed complexes,
M. Eugenia Sanz (1822396), Santiago Mata (1291548), Carlos Cabezas (1291551), José L. Alonso (1291563), Vanesa Vaquero (1822399), Juan C. López (1291557), Isabel Peña (1291545)   +6 more
core   +1 more source

Evaluation of the corrosion inhibitive performance of simple amino acids on copper in a choline chloride/ethylene glycol deep eutectic solvent

Zanco Journal of Pure and Applied Sciences
The electrochemical behavior of copper in choline chloride/ethylene glycol (Ethaline), a deep eutectic solvent (DES), and its amino acid-inhibited solutions (alanine, glycine, and leucine) was investigated using linear sweep voltammetry (LSV) and ...
Essa Ismaeil Ahmed
doaj   +1 more source

Engineering Metal‐Pocket Cooperativity in Single‐Atom COF Nanozymes for Selective Cascade Catalysis

Advanced Materials, EarlyView.
A multilevel programming strategy is developed to engineer single‐atom COF nanozymes with tunable metal centers and chiral pockets inspired by heme–pocket cooperativity. This approach enables controlled metal–pocket interplay for asymmetric cascade catalysis, delivering high activity, selectivity, and recyclability in an asymmetric oxidation–aldol ...
Ziping Li, Qijun Sun, Yawen Hao, Haotian Wen, Shery Chang, Fengwang Li, Jiangtao Xu, Kang Liang   +7 more
wiley   +1 more source

Alanine scanning.

, 2014
Alanine scanning.
Carmine Marco Morgillo (655613), F. Javier Luque (60532), Aldo Galeone (12060), Alfredo Fusco (13561), Stefania Correale (655612), Bruno Catalanotti (655615), Pierlorenzo Pallante (568843), Laura Zaccaro (633090), Antonella Federico (568845), Emilia Pedone (655614), Ivan de Paola (633086)   +10 more
core   +1 more source

Chiral Alanine Functionalized Perylene Diimides: Supramolecular Self-Assembly and Optical Properties

Molecules
Water-soluble alanine-functionalized perylene diimide derivatives (PDI-Ala) were synthesized by introducing alanine units at the imide positions of the PDI framework.
Di Fan, Fan Qi, Nan Li, Rongli Liu, Haitao Ren, Guodong Fan   +5 more
doaj   +1 more source