Results 141 to 150 of about 464,951 (372)
Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery
Advanced Science, EarlyView.Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou +8 more
wiley +1 more source
Advanced Science, EarlyView.Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu +7 more
wiley +1 more source
The Study of 201TlCl Short-Term Effects on Rat Serum Factors [PDF]
مجله علوم و فنون هستهای, 2011 Tl-201 administration for cardial scan using SPECT has been performed for more than 4 decades, while in Iran it has been produced and used for 17 years.
A.R Jalilian, M Alinejad
doaj
Characteristics of hepatic alanine-glyoxylate aminotransferase in different mammalian species [PDF]
, 1978 T. Noguchi +5 more
openalex +1 more source
Social disruption stress exacerbates alpha-galactosylceramide-induced hepatitis in mice [PDF]
, 2005 Objective: Psychosocial stress has been suggested as a possible aggravating factor in liver diseases, however, the underlying mechanism has yet to be clarified.
Chida, Y, Kubo, C, Sonoda, J, Sudo, N
core
Advanced Science, EarlyView.This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao +14 more
wiley +1 more source
Physical activity and elevated liver enzymes: A cross-sectional study from the PERSIAN Guilan cohort study [PDF]
Caspian Journal of Internal MedicineBackground: Regular physical activity promotes health that can affect liver health, particularly modulating liver enzymes. The objective of this study was to assess the association between physical activities and elevated liver enzyme levels in the ...
Heydar Ali Balou +5 more
doaj
Sources of Error in Spectrophotometric Measurement of Aspartate Aminotransferase and Alanine Aminotransferase Activities in Serum [PDF]
, 1974 Denis O. Rodgerson, Iris Osberg
openalex +1 more source
Serum alanine aminotransferase flares in chronic hepatitis B infection: the good and the bad.
The Lancet Gastroenterology and Hepatology, 2020 M. Ghany +6 more
semanticscholar +1 more source
Advanced Science, EarlyView.In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu +10 more
wiley +1 more source