Results 121 to 130 of about 469,247 (341)

Viral and metabolic factors influencing alanine aminotransferase activity in patients with chronic hepatitis C

, 2006
Background/Aims: In chronic hepatitis C, disease progression and clinical manifestations are heterogenous. To clarify the role and interactions of viral and host factors in inducing liver cell injury, we examined the associations of several virological
OBRIEN CB, BLOTNER S, PRATI D, FARCI, PATRIZIA, GANE E, ZEUZEM S., POCKROS P, SHIFFMAN ML, LARDELLI P, REDDY KR, DIAGO M   +10 more
core   +2 more sources

The Relationship Between Aspartate Aminotransferase To Alanine Aminotransferase Ratio And Metabolic Syndrome In Adolescents In Northeast China

Diabetes, Metabolic Syndrome and Obesity, 2019
Shuang Lin,1,2 Lei Tang,1 Ranhua Jiang,3 Yu Chen,1 Sheng Yang,1 Ling Li,1 Ping Li1 1Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, People’s Republic of China; 2Department of Cardiology ...
Lin S, Tang L, Jiang R, Chen Y, Yang S, Li L, Li P   +6 more
doaj  

Alanine Aminotransferase and 20-Year Risk of Major Chronic Diseases and Death in a Healthy Cohort Aged 30 to 49 Years

Clinical Epidemiology, 2020
Morten Daniel Jensen,1 Torsten Lauritzen,2 Hendrik Vilstrup,1 Peter Jepsen1,3 1Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark; 2Department of Public Health, Research Group for General Practice, University of ...
Jensen MD, Lauritzen T, Vilstrup H, Jepsen P   +3 more
doaj  

AMINOTRANSFERASE ACTIVITY IN THE LIVER OF RAINBOW TROUT (ONCORHYNCHUS MYKISS) UNDER VIRAL INFECTION

Ribogospodarsʹka Nauka Ukraïni, 2015
Purpose. To study the effect of the use of indirect (express-) method for the detection of infectious pancreatic necrosis virus of trout by investigating aspartate aminotransferase and alanine aminotransferase activities in fish liver, as the most ...
L. Dragan, M. Maistrenko, G. Lyubchenko, Yu. Rud, L. Buchatsky   +4 more
doaj   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

Association Between High–Normal Levels of Alanine Aminotransferase and Risk Factors for Atherogenesis

Gastroenterology, 2013
Background & Aims Liver disease has been associated with cardiovascular disorders, but little is known about the relationship between serum levels alanine aminotransferase (ALT) and markers of atherogenesis.
M. Siddiqui, R. Sterling, V. Luketic, P. Puri, R. Stravitz, I. Bouneva, Sherry L Boyett, M. Fuchs, Carol Sargeant, G. Warnick, Shahrzad Grami, A. Sanyal   +11 more
semanticscholar   +1 more source

Association of Alanine Aminotransferase and Periodontitis: A Cross-Sectional Analysis-NHANES 2009-2012

, 1905
Objective. Alanine Aminotransferase is an enzyme associated with not only liver diseases, liver conditions, and metabolic syndrome, but also inflammation. Periodontitis is associated with increased cytokines and other markers of inflammation. The purpose
Sambamoorthi, U, Wiener, R C, Jurevic, R J   +2 more
core   +1 more source

Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? [PDF]

, 2012
Preliminary data mostly from animal models suggest the sST2/IL-33 pathway may have causal relevance for vascular disease and diabetes and thus point to a potential novel inflammatory link to cardiometabolic disease.
Kevin A. Deans (125089), Iain B McInnes, Jennifer S McLean, Darren L. Asquith (125071), Ford Ian, Yoga Nathan (12346540), Miller Ashley M., Helen Turner (125085), McLean, JS, McConnachie, A, Burns Harry, Cavanagh Jonathan, Iain B. McInnes (120290), Yoga N. Velupillai (125087), Cavanagh, Jonathan, Chris J. Packard, Jonathan Cavanagh (125077), Ashley M. Miller (125065), Kevin A. Deans, Chris J. Packard (12592780), Asquith, DL, Asquith Darren L., Welsh, P, Jennifer S. Mclean, G. David Batty (125073), Ford, I, Turner Helen, David Purves, G David Batty, Kevin A. Deans (12592774), McInnes Iain B., Burns, Harry, Paul G Shiels, David Purves (125069), Sattar Naveed, Turner, H, McInnes, Iain B., Darren L Asquith, Darren L. Asquith, Ashley M. Miller, Naveed Sattar (8785), Batty, David G., Harry Burns (125075), McConnachie Alex, Burns, H, McLean, Jennifer S., Sattar, Naveed, McInnes, IB, Jennifer S. McLean (125079), Packard, CJ, Batty G. David, Chris J. Packard (125081), Batty, GD, Darren L . Asquith (12597775), Shiels, Paul G., Shiels, PG, G. David Batty, McLean Jennifer S., Sattar, N, Chris J Packard, Ian Ford, Alex McConnachie (104022), Welsh, Paul, Welsh Paul, Ashley M Miller, Purves David, Deans Kevin A., Velupillai, YN, Jennifer S. McLean (12592768), Miller, Ashley M., Ian Ford (30666), Purves, D, Velupillai Yoga N., McConnachie, Alex, Deans, KA, Naveed Sattar, Turner, Helen, Paul G. Shiels (12592783), Ashley M. Miller (12597772), Ford, Ian, Shiels Paul G., Paul Welsh (125091), Kevin A Deans, Paul G. Shiels, Jonathan Cavanagh, Asquith, Darren L., Deans, Kevin A., Paul Welsh, Paul G. Shiels (125083), Iain B. Mcinnes, Alex McConnachie, Helen Turner, Asquith, Darren L ., David G. Batty (12592771), Cavanagh, J, Nathan, Yoga, Yoga N Velupillai, Velupillai, Yoga N., Harry Burns, Packard Chris J., Miller, AM, Packard, Chris J., Purves, David, Batty, G. David, Yoga N. Velupillai   +104 more
core   +1 more source

Biomimetic Polymerization of Tellurocysteine: Breaking the Natural Amino Acid Radioprotection Limitation

Advanced Science, EarlyView.
Inspired by natural amino acid polymer‐melanin systems, this study strategically incorporated tellurocysteine to develop advanced radiation‐shielding materials. This approach transformed the primary interaction mechanism between melanin‐based materials and incident photons from Compton scattering to the photoelectric effect. Tellurocysteine‐polymerized
Wei Chen, Hanjie Zhu, Yue Zhang, Yuqing Qiao, Ruotong Deng, Huaping Xu, Wei Cao   +6 more
wiley   +1 more source

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

Advanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng, Jiahao Lin, Qiushuang Zhang, Xiangdong Zhang, Yicong Dai, Jinghong Li   +5 more
wiley   +1 more source