Results 71 to 80 of about 457,916 (395)

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

Arthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp, Anne Horne, Borislav Mihov, Jill Drake, Janine Haslett, Peter Chapman, Daniel F. B. Wright, Christopher Frampton, Nicola Dalbeth   +8 more
wiley   +1 more source

Serum alanine aminotransferase/aspartate aminotransferase ratio is one of the best markers of insulin resistance in the Chinese population

Nutrition and Metabolism, 2017
BackgroundThe alanine aminotransferase (ALT)/aspartate aminotransferase (AST) ratio is reportedly associated with insulin resistance (IR). However, few studies have explored the relationship between the ALT/AST ratio and IR in the Chinese population ...
Li Zhao, Jing Cheng, Yingchao Chen, Qin Li, B. Han, Yi Chen, F. Xia, Chi Chen, D. Lin, Xuemei Yu, Ningjian Wang, Yingli Lu   +11 more
semanticscholar   +1 more source

A Novel Protein‐Polysaccharide Oral Nanoemulsion Targeting Activated Hepatic Stellate Cells to Enhance the Therapeutic Effect of Pirfenidone on Fibrosis After Transarterial Chemoembolization for Liver Cancer

Advanced Functional Materials, EarlyView.
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng, Shan Xu, Yi Lei, Huizhou He, Runbin Sun, Xingle Jin, Cheneryu Huang, Yuhao Zheng, Jianqing Peng, Lei Tang, Peng Luo, Yi Chen, Shuai Zhang   +12 more
wiley   +1 more source

Lighter serum copper isotopic composition in patients with early non-alcoholic fatty liver disease [PDF]

, 2020
Objective The occurrence of non-alcoholic fatty liver disease (NAFLD) is globally increasing. To challenge the current incidence of NAFLD, non-invasive markers that could identify patients at risk or monitor disease progression are an important need ...
Costas Rodriguez, Marta, Devisscher, Lindsey, Hastuti, Agustina Ari Murti Budi, Lefere, Sander, Van Campenhout, Sanne, Van Vlierberghe, Hans, Vanhaecke, Frank   +6 more
core   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

Low aspartate aminotransferase/alanine aminotransferase (DeRitis) ratio assists in predicting diabetes in Chinese population

Frontiers in Public Health, 2022
BackgroundFew studies discussed the predictive ability of aspartate aminotransferase/alanine aminotransferase (AST/ALT, DeRitis) ratio for diabetes risk.
Wangcheng Xie, Weidi Yu, Shanshan Chen, Zhilong Ma, Tingsong Yang, Zhenshun Song   +5 more
doaj   +1 more source

Perbedaan Kadar Alanine Aminotransferase (Alt) Dalam Serum Dari Darah Yang Disentrifugasi Pada Kecepatan 3000 Rpm Selama 5 Menit Dan 4400 Rpm Selama 3 Menit [PDF]

, 2019
Background : Laboratory tests for liver and heart are emergency, so the examination must be carried out quickly including ALT examination. One way is by reducing the time of centrifugation without reducing the quality of serum.
.,, Suryani
core  

Hepatic infarction following abdominal interventional procedures. [PDF]

, 2004
To clarify the incidence, background, and progress of hepatic infarction following interventional procedures, cases of hepatic infarction following interventional procedures at our department during the last decade were identified by reviewing the ...
Akaki, Shiro, Fujiwara, Hiroyasu, Hiraki, Takao, Hiraki, Yoshio, Kanazawa, Susumu, Mimura, Hidefumi, Naomoto, Yoshio, Tanaka, Noriaki, Yagi, Takahito, Yasui, Kotaro   +9 more
core   +1 more source

The aspartate aminotransferase-to-alanine aminotransferase ratio predicts all-cause and cardiovascular mortality in patients with type 2 diabetes

Medicine, 2016
An increased aspartate aminotransferase-to-alanine aminotransferase ratio (AAR) has been widely used as a marker of advanced hepatic fibrosis. Increased AAR was also shown to be significantly associated with the risk of developing cardiovascular (CV ...
G. Zoppini, V. Cacciatori, C. Negri, Vincenzo Stoico, G. Lippi, G. Targher, E. Bonora   +6 more
semanticscholar   +1 more source

Self‐Cascade Catalytic Reaction–Assisted Apoptosis/Calcicoptosis/Ferroptosis Induction with Microsphere‐Aggregated Hydrogels in Triple‐Negative Breast Cancer Therapy

Advanced Functional Materials, EarlyView.
Hyaluronic acid‐dopamine‐based intra‐crosslinked microsphere including cisplatin (HPC MS) is fabricated by spray‐drying and calcium/iron ions are introduced for interparticle crosslinking. Designed microsphere‐aggregated hydrogel (MAH) system including cisplatin/CaO2/FeSO4 can provide apoptosis/calcicoptosis/ferroptosis‐mediated chemo/cascade ...
ChaeRim Hwang, Yeoung Eun Choi, Song Yi Lee, Mrinmoy Karmakar, Qiaojun Hao, Junmin Lee, Hyun‐Jong Cho   +6 more
wiley   +1 more source