Results 81 to 90 of about 457,916 (395)

Study of the chemical evolution and spectral signatures of some interstellar precursor molecules of adenine, glycine alanine [PDF]

2013NewA...20...15M, 2012
We carry out a quantum chemical calculation to obtain the infrared and electronic absorption spectra of several complex molecules of the interstellar medium (ISM). These molecules are the precursors of adenine, glycine & alanine. They could be produced in the gas phase as well as in the ice phase.
arxiv   +1 more source

Identification and expression analyses of the alanine aminotransferase (AlaAT) gene family in poplar seedlings

Scientific Reports, 2017
Alanine aminotransferase (AlaAT, E.C.2.6.1.2) catalyzes the reversible conversion of pyruvate and glutamate to alanine and α-oxoglutarate. The AlaAT gene family has been well studied in some herbaceous plants, but has not been well characterized in woody
Zhiru Xu, Jing Ma, Chunpu Qu, Yanbo Hu, Bingqing Hao, Yan Sun, Zhongye Liu, Han Yang, Chengjun Yang, Hongwei Wang, Ying Li, Guanjun Liu   +11 more
semanticscholar   +1 more source

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

Hepatitis induced by noni juice from Morinda citrifolia: A rare cause of hepatotoxicity or the tip of the iceberg? [PDF]

, 2006
A 24-year-old female patient presented to her community hospital with mild elevations of serum transaminase and bilirubin levels. Because of multiple sclerosis, she was treated with interferon beta-la for 6 weeks.
Diebold, J., Gerbes, Alexander L., Gülberg, Veit, Yuece, B.   +3 more
core   +1 more source

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

Advanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao, Maoze Wang, Jinling Huang, Yu Wang, Jing Zhao, Ran Wang, Zhi Ping Xu, Jianping Jiang, Lingxiao Zhang   +8 more
wiley   +1 more source

Association of Alanine Aminotransferase and Periodontitis: A Cross-Sectional Analysis—NHANES 2009–2012

International Journal of Inflammation, 2016
Objective. Alanine Aminotransferase is an enzyme associated with not only liver diseases, liver conditions, and metabolic syndrome, but also inflammation. Periodontitis is associated with increased cytokines and other markers of inflammation. The purpose
R. Constance Wiener, Usha Sambamoorthi, Richard J. Jurevic   +2 more
doaj   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

The effect of 8 weeks of circuit training on body weight, blood pressure, serum Cholesterol levels and liver enzymes in elderly women with metabolic syndrome [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2019
Introduction: Inactive lifestyle is a very important risk factor for the development of many diseases, including metabolic syndrome. In aging, in addition to aging-related problems, some elderly people develop metabolic syndrome, which is more common in ...
Zahra Nourollahi, Vahid Valipour Dehnou, Rasoul Eslami   +2 more
doaj   +1 more source

Piper crocatum Ameliorates APAP-Induced Hepatotoxicity through Antioxidant and Anti-Inflammatory Mechanisms

Journal of Mathematical and Fundamental Sciences, 2022
Cirrhosis is a serious hepatic disease that occurs worldwide and is caused by progressive fibrosis in the liver. Free radicals are the major cause of reactive oxygen species (ROS) generation, which affects the balance of the liver metabolism.
I Nyoman Ehrich Lister, Chrismis Novalinda Ginting, Ermi Girsang, Adek Amansyah, Linda Chiuman, Ni Luh Wisma Eka Yanti, Wahyu Setia Widodo, Dewani Tediana Yusepany, Rizal Rizal, Wahyu Widowati   +9 more
doaj   +1 more source

Global and Local Interpretation of black-box Machine Learning models to determine prognostic factors from early COVID-19 data [PDF]

arXiv, 2021
The COVID-19 corona virus has claimed 4.1 million lives, as of July 24, 2021. A variety of machine learning models have been applied to related data to predict important factors such as the severity of the disease, infection rate and discover important prognostic factors.
arxiv