Alanine Represses γ-Aminobutyric Acid Utilization and Induces Alanine Transaminase Required for Mitochondrial Function in Saccharomyces cerevisiae [PDF]
The γ-aminobutyric acid (GABA) shunt constitutes a conserved metabolic route generating nicotinamide adenine dinucleotide phosphate (NADPH) and regulating stress response in most organisms.
Dariel Márquez+5 more
doaj +3 more sources
Prognostic Role of Pretreatment De Ritis Ratio (Aspartate Transaminase/Alanine Transaminase Ratio) in Urological Cancers: A Systematic Review and Meta-Analysis [PDF]
Background: To examine the potential prognostic significance of pretreatment De Ritis ratio (aspartate transaminase/alanine transaminase ratio) in urological cancers, including upper tract urothelial cancer (UTUC), renal cell carcinoma (RCC), prostate ...
Shiqiang Su+4 more
doaj +3 more sources
Prognostic Value of Aspartate Transaminase/Alanine Transaminase Ratio in Patients With Hepatitis B Virus-Related Hepatocellular Carcinoma Undergoing Hepatectomy [PDF]
BackgroundAspartate transaminase/alanine transaminase (De Ritis) ratio is a good predictor of liver function damage, but its prognostic value in patients with hepatocellular carcinoma (HCC) undergoing hepatectomy remains unclear.
Qiuyan Mo+13 more
doaj +3 more sources
The association of aspartate transaminase-to-alanine transaminase ratio and metabolic syndrome among HIV patients in Sidama Region, South Ethiopia [PDF]
Objective: Studies on the association of the aspartate transaminase-to-alanine transaminase ratio with the metabolic syndrome and its components among HIV patients were scarce.
Wondwossen Abera+2 more
doaj +2 more sources
The Effect of Elevated Alanine Transaminase on Non-invasive Prenatal Screening Failures [PDF]
ObjectiveTo determine the effects of alanine transaminase (ALT) levels on the screening failure rates or “no calls” due to low fetal fraction (FF) to obtain a result in non-invasive prenatal screening (NIPS).MethodsNIPS by sequencing and liver enzyme ...
Ping Chen+11 more
doaj +2 more sources
A Rise in Aspartate Transaminase and Alanine Transaminase Associated With Ondansetron Administration in a Pregnant Female. [PDF]
Ondansetron (ODSN) is a commonly used and well-tolerated anti-emetic used during pregnancy. Upon review, three cases were identified in which liver function tests (LFTs) were elevated after ODSN administration without concurrent chemotherapy. In this report, we present a case of a 28-year-old pregnant female experiencing psychosis who developed serum ...
Couse M, Syed S.
europepmc +7 more sources
GLUCOCORTICOID STIMULATION OF THE BIOSYNTHESIS OF GLUTAMIC-ALANINE TRANSAMINASE [PDF]
Results.-In order to interpret meaningfully the results of measurements of the influence of hormones on amino acid incorporation into a specific protein, it is necessary to know that the period of exposure to the labeled amino acid is short relative to the half-life of the enzyme.
Harold L. Segal, Yee S. Kim
openalex +5 more sources
Development of prediction model for alanine transaminase elevations during the first 6 months of conventional synthetic DMARD treatment. [PDF]
Kuusalo L+5 more
europepmc +3 more sources
Isocitritase, Glycine-Alanine Transaminase, and Development in Blastocladiella Emersonii [PDF]
Howard D. McCurdy, Edward C. Cantino
openalex +5 more sources
Preoperative aspartate transaminase/alanine transaminase ratio as a prognostic biomarker in primary non-muscle-invasive bladder cancer: a propensity score-matched study. [PDF]
Cheng X+5 more
europepmc +3 more sources