Results 131 to 140 of about 196,626 (324)

Association of alanine transaminase to aspartate aminotransferase ratio and incident diabetes in Chinese adults: a second retrospective cohort study [PDF]

, 2020
Zhilin Liang, Haofei Hu, Xunxun Wang, Xianxiong Chen, Min Zhang, Zhigang Liu   +5 more
openalex   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Effect of Dietary Supplementation of Polyalthia longifolia Leaf Meal on Alanine Transaminase (ALT) and Aspartate Transaminase (AST) Levels in Broiler Chicken [PDF]

, 2017
Chinnapaiyan Srinivasan, P. Gangadevi, K. Ally, Deepa Ananth, Binoj Chacko, P Sathya   +5 more
openalex   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Metabolically driven equilibrium shift of asymmetric amination of ketones by ω-transaminase using alanine as an amino donor [PDF]

, 2014
Sang‐Woo Han, Jong‐Shik Shin
openalex   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids. [PDF]

Cell Rep, 2022
Martino MR, Gutiérrez-Aguilar M, Yiew NKH, Lutkewitte AJ, Singer JM, McCommis KS, Ferguson D, Liss KHH, Yoshino J, Renkemeyer MK, Smith GI, Cho K, Fletcher JA, Klein S, Patti GJ, Burgess SC, Finck BN.   +16 more
europepmc   +2 more sources

Normal Range of Serum Alanine Aminotransferase (ALT) Levels in Healthy Population of Yazd and Relation to Demographic Factors

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2010
Introduction: Alanine aminotransferase (ALT) is the most useful laboratory marker of hepatic necroinflammation that is used for diagnosis of liver diseases. Based on recent data, the investigators suggested a new upper limit of normal, which was based on
M Askarzadeh, N Bashardoost, M Akhondi-Meybodi, M Amir-Baygi   +3 more
doaj  

Metabolic Factors Associated with Alanine Transaminase Levels in Non-Alcoholic Fatty Liver Disease

Proceedings
Background: Non-Alcoholic Fatty Liver Disease is the most increasing chronic liver condition with a global prevalence of 30%. Metabolic factors like Obesity, Diabetes Mellitus are considered as major risk factors.
Safwa Mahmood, Minahil Atique, Amir Rafeeq, Aaman Inaam Khan, Safwa Mahmood, Maham Akhlaq   +5 more
doaj   +3 more sources

Cholecystitis & An Enzyme Study [PDF]

, 2011
Cholecystitis is inflammation of the gallbladder that develops in short time usually when gallstone obstructs the cystic duct. Patients over the passage of time land to chronic cholecystitis.
Anil Batta, Int J Cur Biomed Phar Res.
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