JGH Open, 2020 Background and Aim Marked elevations of alanine aminotransferase (ALT) are caused by a limited number of underlying pathologies, including hepatic ischemia, drugs/toxins, viral hepatitis, and—rarely—autoimmune hepatitis.
Danny Con +3 more
doaj +1 more source
Diagnostic accuracy of liver stiffness measurement in chronic hepatitis B patients with normal or mildly elevated alanine transaminase levels. [PDF]
Sci Rep, 2018 We aimed to evaluate the diagnostic accuracy of liver stiffness measurement (LSM) in 188 chronic hepatitis B (CHB) patients with alanine transaminase (ALT) ≤ twice the upper limit of normal (ULN).
Li Q, Chen L, Zhou Y.
europepmc +2 more sources
Prognostic Potential of Liver Enzymes in Patients With COVID-19 at the Leishenshan Hospital in Wuhan
Frontiers in Cellular and Infection Microbiology, 2021 BackgroundCoronavirus disease 2019 (COVID-19) has evolved into a pandemic. We hypothesized that biochemical indicators of liver function may help determine the prognosis of COVID-19 patients.MethodsPatient information was collected from the Wuhan ...
Zeming Liu +11 more
doaj +1 more source
A novel diagnostic algorithm to predict significant liver inflammation in chronic hepatitis B virus infection patients with detectable HBV DNA and persistently normal alanine transaminase. [PDF]
Sci Rep, 2018 Significant liver inflammation might be found in 20–34% of chronic hepatitis B virus (HBV) infection patients with detectable HBV DNA and persistently normal alanine transaminase (ALT) (PNALT).
Li Q, Zhou Y, Huang C, Li W, Chen L.
europepmc +2 more sources
Effect of anti-retroviral therapy on oxidative stress in hospitalized HIV-infected adults with and without TB. [PDF]
, 2018 BackgroundHIV infection and opportunistic infections cause oxidative stress (OS), which is associated with tissue damage. Anti-retroviral therapy (ART) is used to treat HIV and decrease the risk of opportunistic infections, but it is unclear whether ART ...
Andama, Alfred +14 more
core +3 more sources
The Association of Alanine Transaminase With Aging, Frailty, and Mortality [PDF]
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2010 The relationships between blood tests of liver function and injury (alanine transaminase [ALT], gamma-glutamyl transferase, bilirubin, and albumin) with age, frailty, and survival were investigated in 1,673 community-dwelling men aged 70 years or older. ALT was lower in older participants.
Fiona M. Blyth +8 more
openaire +3 more sources
Frontiers in Microbiology, 2017 Gene duplication is one of the major evolutionary mechanisms providing raw material for the generation of genes with new or modified functions. The yeast Saccharomyces cerevisiae originated after an allopolyploidization event, which involved mating ...
Ximena Escalera-Fanjul +5 more
doaj +1 more source
Upper Limit of Normal for Serum Alanine Transaminase in Healthy Population. [PDF]
Indian J Clin Biochem, 2018 Joob B, Wiwanitkit V.
europepmc +5 more sources
Rational design of a (S)-selective-transaminase for asymmetric synthesis of (1S)-1-(1,1′-biphenyl-2-yl)ethanamine [PDF]
, 2016 Amine transaminases offer an environmentally sustainable synthesis route for the production of pure chiral amines. However, their catalytic efficiency toward bulky ketone substrates is greatly limited by steric hindrance and therefore presents a great ...
Allen, Christopher C.R. +12 more
core +3 more sources
3-Hydroxykynurenine Transaminase Identity with Alanine Glyoxylate Transaminase [PDF]
Journal of Biological Chemistry, 2002 This study describes the functional characterization of a specific mosquito transaminase responsible for catalyzing the transamination of 3-hydroxykynurenine (3-HK) to xanthurenic acid (XA). The enzyme was purified from Aedes aegypti larvae by ammonium sulfate fractionation, heat treatment, and various chromatographic techniques, plus non-denaturing ...
Qian Han, Jianyong Li, Jianmin Fang
openaire +3 more sources