Results 61 to 70 of about 175,083 (295)

Gallbladder perforation during elective laparoscopic cholecystectomy: Incidence, risk factors, and outcomes

open access: yesİstanbul Kuzey Klinikleri, 2018
INTRODUCTION[|]This study aimed to reveal the risk factors and outcomes of gallbladder perforation (GP) during laparoscopic cholecystectomy.[¤]METHODS[|]Videotapes of all patients who underwent an elective cholecystectomy at our department were ...
Yunus Emre Altuntas   +6 more
doaj   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao   +11 more
wiley   +1 more source

EFFICACY OF SALICYLIC AND ASCORBIC ACIDS TO REDUCE THE EFFECT OF TRANSPORT STRESS ON LIVE WEIGHT, SOME BLOOD CHARACTERISTICS AND INTESTINAL VILLI OF BROILER CHICKENS

open access: yesThe Iraqi Journal of Agricultural science, 2020
This experiment was conducted and aimed to reducing mortality and losing the weight of birds transported to the slaughter house through reducing or Transport stress removal and thus to reduce financial losses.
Al obaydy & et al.
doaj  

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

open access: yesAdvanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao   +7 more
wiley   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

open access: yesAdvanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang   +11 more
wiley   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

Alanine amino transferase (ALT) specific activities in long term systemic hypoxic rat brain tissues

open access: yesActa Biochimica Indonesiana, 2019
Background: Brain as a very aerobic organ is sensitive to hypoxia. Energy scarcities must be overcome by gluconeogenesis, which uses alanine or lactate as starting material.
Rizka Ramadhani, Ani Retno Prijanti
doaj   +1 more source

PENGARUH MINUMAN GULA BERKARBONASI TERHADAP KADAR ASPARTATE TRANSAMINASE DAN ALANINE TRANSAMINASE - Studi Eksperimental pada Tikus Putih (Rattus novergicus) Galur Wistar [PDF]

open access: yes, 2014
Minuman gula berkarbonasi dapat menyebabkan gangguan pada hati jika dikonsumsi berlebihan. Hal tersebut dapat mempengaruhi kadar Aspartate transaminase (AST) dan Alanine transaminase (ALT).
Utama, Dirgantara Aliif
core  

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

open access: yes
Arthritis Care &Research, EarlyView.
Catherine Deffendall   +6 more
wiley   +1 more source

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

open access: yesAdvanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang   +10 more
wiley   +1 more source

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