Results 81 to 90 of about 321,126 (349)

Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium. [PDF]

, 2019
ObjectivePopulations of Mexican American ancestry are at an increased risk for nonalcoholic fatty liver disease. The objective of this study was to determine whether loci in known and novel genes were associated with variation in aspartate ...
Chen, Yii-Der I, Fingerlin, Tasha E, Goodarzi, Mark O, Guo, Xiuqing, Langefeld, Carl D, Norris, Jill M, Palmer, Nicholette D, Raffel, Leslie J, Rotter, Jerome I, Taylor, Kent D, Wagenknecht, Lynne E, Wang, Nan, Watanabe, Richard M, Williams, Adrienne H, Xiang, Anny H, Young, Kendra A   +15 more
core   +2 more sources

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

Arthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp, Anne Horne, Borislav Mihov, Jill Drake, Janine Haslett, Peter Chapman, Daniel F. B. Wright, Christopher Frampton, Nicola Dalbeth   +8 more
wiley   +1 more source

Changes in Alanine transaminase levels in response to statins: Sri Lankan experience in patient with type 2 Diabetes mellitus with Dyslipidemia

Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2018
Background:Statins form the pharmacologic cornerstone of the primary and secondary prevention of atherosclerotic cardiovascular disease. While statins are well-tolerated by most people, the most common adverse effect is the asymptomatic elevation of ...
C.N. Antonypillai, W.C.K. Jayawardena, I.G. Samarakkody, S. Dahanayake, L. Monaragala, D.L.N. Wijerathne, T.L. Dassanayake   +6 more
doaj   +1 more source

The Importance of De Ritis Ratio in Patients with Bladder Cancer

Bagcilar Medical Bulletin, 2020
Objective:Numerous studies prove the relationship between serum aspartate transaminase/alanine transaminase (AST/ALT) ratio (De Ritis Ratio) and cancer cases.
Kasım Ertaş, Recep Eryılmaz, Rahmi Aslan, Murat Demir, Kerem Taken   +4 more
doaj   +1 more source

Effects of Emulsion Formulations of Oleuropein Isolated from Ethanol Extract of Olive Leaf in Diabetic Rats [PDF]

Anais da Academia Brasileira de Ciências, 2020
This study was designed to investigate the effects of emulsion formulations of oleuropein isolated from ethanol extract of olive leaf in streptozotocin-diabetic rats.
AHMET G. AGGUL, MINE GULABOGLU, MELTEM CETIN, EMRAH OZAKAR, RUKIYE S. OZAKAR, TUBA AYDIN   +5 more
doaj   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

Integrating gene and protein expression data with genome-scale metabolic networks to infer functional pathways [PDF]

, 2013
This article has been made available through the Brunel Open Access Publishing Fund. Copyright @ 2013 Pey et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://
Beasley, JE, Pey, J, Planes, FJ, Rubio, A, Valgepea, K   +4 more
core   +1 more source

Self‐Cascade Catalytic Reaction–Assisted Apoptosis/Calcicoptosis/Ferroptosis Induction with Microsphere‐Aggregated Hydrogels in Triple‐Negative Breast Cancer Therapy

Advanced Functional Materials, EarlyView.
Hyaluronic acid‐dopamine‐based intra‐crosslinked microsphere including cisplatin (HPC MS) is fabricated by spray‐drying and calcium/iron ions are introduced for interparticle crosslinking. Designed microsphere‐aggregated hydrogel (MAH) system including cisplatin/CaO2/FeSO4 can provide apoptosis/calcicoptosis/ferroptosis‐mediated chemo/cascade ...
ChaeRim Hwang, Yeoung Eun Choi, Song Yi Lee, Mrinmoy Karmakar, Qiaojun Hao, Junmin Lee, Hyun‐Jong Cho   +6 more
wiley   +1 more source

Comparison of deferasirox and deferoxamine effect on liver enzyme activities and ferritin level in patients with beta-thalassemia

Zanco Journal of Medical Sciences, 2020
Background and objective: Patients on blood transfusion may develop complications related to iron overload and the effects of chelating agents (drugs), which adversely affect the liver in thalassemia, which is a genetic blood disorder of hemoglobin ...
Rasul Jameel Ali, Dler Rostum Ali, Zhyan Ismail Ahmed, Amal Aziz Ahmed, Dilvin Saleh Hassen, Rozy Mohammed Tahir   +5 more
doaj   +1 more source

Effect of levamisole, Vitamin E, and selenium against aflatoxicosis in broilers chicken [PDF]

Veterinary World, 2018
Aim: The experiment was conducted to determine of levamisole (0.2 ml/kg-BW), Vitamin E (80 mg)+selenium (1.6 mg), and aflatoxin (B1) (positive control) compared with group without aflatoxin (negative control) on some liver enzymes (aspartate transaminase
Amjed H. Ulaiwi
doaj   +1 more source