Results 251 to 260 of about 129,755 (297)

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang   +14 more
wiley   +1 more source

Acid ceramidase overactivity drives ceramide loss, leading to atopic dry skin and Th2‐skewed immune polarization

open access: yesThe Journal of Pathology, Volume 269, Issue 2, Page 232-247, June 2026.
Abstract Ceramide deficiency in the stratum corneum (SC) is a key etiological factor in atopic dermatitis (AD). To clarify the direct role of SC ceramide depletion in impairing SC barrier and water‐holding functions and in initiating AD‐like skin symptoms and disease‐specific molecular alterations, we generated Tg mice overexpressing a mutant form of ...
Mariko Takada   +8 more
wiley   +1 more source

Structural analysis of Cu/Zn‐superoxide dismutase linked to neurodegenerative disease by antibody‐guided cryo‐EM

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Accumulation of misfolded proteins is a hallmark of many neurodegenerative diseases. To characterize such misfolded species in vivo, conformation‐specific antibodies are widely used; however, limited knowledge of antibody–epitope interactions often hampers mechanistic insight.
Yuki Shino   +7 more
wiley   +1 more source

Severe hepatic lipidosis in a dog: a case report. [PDF]

open access: yesVet Res Forum
Abbasi F   +5 more
europepmc   +1 more source

Development and characterization of near‐isogenic lines for quantitative trait locus qDT.3B.1 underlying drought tolerance in wheat

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Drought is a critical challenge to wheat (Triticum aestivum L.) productivity. The quantitative complexity of drought tolerance makes breeding for this trait difficult. Developing near‐isogenic lines (NILs) targeting quantitative trait locus (QTL) for 1000‐grain weight (TGW) under drought stress can effectively identify key mechanisms and genes.
Joanne D. Caguiat   +4 more
wiley   +1 more source

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