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Severe Hepatocellular Injury With Transaminases > 20,000 IU/L in Suspected Repeated Drug Ingestion Despite Undetectable Serum Levels. [PDF]
CureusPatel V, Khan RS, Rangasamy A, Shah R.
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Metabolic profiles and hepatic steatosis assessed by controlled attenuation parameter and elastography during Ramadan fasting in San Antonio, United States. [PDF]
World J RadiolJamil J +7 more
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Ferritin as a novel predictive index for nasopharyngeal carcinoma survival and therapeutic efficacy of different chemotherapy regimens. [PDF]
World J Clin OncolTang Q, Wu Y, Chen L, Jia QY, Tang FQ.
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High performance liquid chromatography assay for alanine amino transferase
Chromatographia, 1991An improved method of alanine-amino transferase determination is proposed. The reaction is carried out with alanine and 2-oxoglutarate as substrates and analysis is by HPLC on a reversed-phase chromatographic system using a C18 column and tetrabutylammonium phosphate in phosphate buffer (pH 7.0)-acetonitrile as mobile phase.
Silvia Canepari
exaly +3 more sources
Inactive and active alanine 2-oxoglutarate amine transferase in maize embryo
Phytochemistry, 1977Abstract Freshly prepared extracts of maize embryo exhibited a rise of alanine 2-oxoglutarate amine transferase activity when they were treated at temperatures ranging from 35 to 50° before the assay of the enzyme. The same rise of activity was observed when the extracts were incubated at 25° in the presence of alanine.
Bartolome Sabater
exaly +2 more sources
Upper limit of plasma alanine amino transferase during Phase I studies
European Journal of Clinical Pharmacology, 1995In Phase I clinical studies, the maximum tolerated dose has to be determined by a case by case analysis sometimes using a laboratory adverse effect, e.g. an increase in alanine amino transferase (ALT). For this reason a threshold to discriminate between significant or non significant adverse changes in ALT is required particularly in Phase I studies ...
M, Sibille +5 more
exaly +3 more sources
Clinical Biochemistry, 2000
To study whether determining alpha-glutathione S-transferase (alpha-GST) might improve the assessment of chronic hepatitis C (CHC) patients with near normal alanine aminotransferase levels (NNA).We studied 119 viraemic CHC patients. They were subdivided into two groups according to the pattern of alanine aminotransferase (ALT) alteration, i.e ...
Edoardo G. Giannini
exaly +4 more sources
To study whether determining alpha-glutathione S-transferase (alpha-GST) might improve the assessment of chronic hepatitis C (CHC) patients with near normal alanine aminotransferase levels (NNA).We studied 119 viraemic CHC patients. They were subdivided into two groups according to the pattern of alanine aminotransferase (ALT) alteration, i.e ...
Edoardo G. Giannini
exaly +4 more sources
Clinical Chemistry and Laboratory Medicine, 2013
Abstract Background: Alanine aminotransferase (ALT), aspartate aminotransferase (AST) and γ-glutamyl transferase (GGT) are enzymes measured in serum or plasma to investigate liver disease. The aim of this work is to assess the validity of published biological variation (BV) data currently available for these enzymes.
Anna Carobene +2 more
exaly +5 more sources
Abstract Background: Alanine aminotransferase (ALT), aspartate aminotransferase (AST) and γ-glutamyl transferase (GGT) are enzymes measured in serum or plasma to investigate liver disease. The aim of this work is to assess the validity of published biological variation (BV) data currently available for these enzymes.
Anna Carobene +2 more
exaly +5 more sources