Results 191 to 200 of about 1,044,683 (223)

Nanoparticle Albumin-Bound Paclitaxel (Abraxane®)

2016
Albumin has high binding affinity to hydrophobic molecules and is highly accumulated in tumors, making it an ideal carrier to transport water insoluble drugs to tumors. Nanoparticle albumin-bound (nab®) technology is an albumin-based nanoparticle drug delivery platform that preferentially delivers albumin-bound hydrophobic drugs to tumors without using
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Cystoid Macular Edema Secondary to Nanoparticle Albumin-Bound Paclitaxel Therapy

Ophthalmic Surgery, Lasers and Imaging Retina, 2013
The authors report a case of nanoparticle albumin-bound paclitaxel-induced cystoid macular edema (CME) without fluorescein angiographic leakage in a patient being treated for metastatic breast cancer. The CME briskly improved 3 weeks after the chemotherapeutic agent was discontinued and was completely resolved after 6 weeks.
Ehsan, Rahimy, David, Sarraf
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Nanoparticle Albumin-Bound Paclitaxel: A Novel Cremphor-EL ^® -Free Formulation of Paclitaxel

Nanomedicine, 2007
Standard formulation paclitaxel requires the use of solvents, such as Cremphor-EL, which contribute to some of the toxicities commonly associated with paclitaxel-based therapy. Nanoparticle albumin-bound paclitaxel (nab-paclitaxel) is a novel solvent-free formulation of paclitaxel.
openaire   +2 more sources

Albumin-Bound Paclitaxel In Metastatic Breast Cancer

Drugs, 2006
Mark Harries, Peter Harper
  +4 more sources

Nanoparticle albumin-bound paclitaxel (nab-Paclitaxel): Bridging pharmacology and translational medicine in breast cancer

Current Research in Translational Medicine
Nanoparticle albumin-bound paclitaxel (nab-paclitaxel) represents a significant advancement in breast cancer therapy by enhancing drug delivery and minimizing solvent-related toxicity. Utilizing albumin-mediated transcytosis, nab-paclitaxel achieves superior intratumoral accumulation while eliminating hypersensitivity reactions linked to solvent-based ...
Ali G, Alkhathami, Abdulrahman T, Ahmed, Ahmed, Hussein, Roopashree, R, Prakhar, Tomar, Hussein Riyadh Abdul Kareem, Al-Hetty, Rajashree, Panigrahi, Ashish Singh, Chauhan, Fathi Jihad, Hammady, Salah Abdulhadi, Salih   +9 more
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Paclitaxel (albumin-bound)

2021
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Albumin-Bound Paclitaxel plus Gemcitabine in Pancreatic Cancer

New England Journal of Medicine, 2014
Daniel D, Von Hoff, David, Goldstein, Markus F, Renschler   +2 more
openaire   +4 more sources

Reassembling of albumin-bound paclitaxel mitigates myelosuppression and improves its antitumoral efficacy via neutrophil-mediated targeting drug delivery

Drug Delivery, 2022
Gang Wang, Dafei Chai, Yu-Xin Chen
exaly  

Albumin-bound paclitaxel (Abraxane) for advanced breast cancer.

The Medical letter on drugs and therapeutics, 2005
A new formulation that should be safer and easier to administer than Taxol.
openaire   +1 more source

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Frontiers in Oncology, 2022
Zhichao Tian
exaly