Results 1 to 10 of about 3,637,487 (305)

Association of Superoxide Dismutase 2 (SOD2) Genotype with Gray Matter Volume Shrinkage in Chronic Alcohol Users: Replication and Further Evaluation of an Addiction Gene Panel. [PDF]

, 2016
BackgroundReduction in brain volume, especially gray matter volume, has been shown to be one of the many deleterious effects of prolonged alcohol consumption. High variance in the degree of gray matter tissue shrinkage among alcohol-dependent individuals
Gitik, Miri, Goldman, David, Hodgkinson, Colin A, Meyerhoff, Dieter J, Shen, Pei-Hong, Srivastava, Vibhuti   +5 more
core   +1 more source

The Community-Based Medication-First program for opioid use disorder: a hybrid implementation study protocol of a rapid access to buprenorphine program in Washington State

Addiction Science & Clinical Practice, 2022
Background Opioid use disorder (OUD) is a serious health condition that is effectively treated with buprenorphine. However, only a minority of people with OUD are able to access buprenorphine.
Caleb J. Banta-Green, Mandy D. Owens, Jason R. Williams, Jeanne M. Sears, Anthony S. Floyd, Wendy Williams-Gilbert, Susan Kingston   +6 more
doaj   +1 more source

Chronic Binge Alcohol and Ovarian Hormone Loss Dysregulate Circulating Immune Cell SIV Co-Receptor Expression and Mitochondrial Homeostasis in SIV-Infected Rhesus Macaques

Biomolecules, 2022
Effective antiretroviral therapy (ART) has transitioned HIV to a chronic disease, with more than 50% of people living with HIV (PLWH) being over the age of 50.
Patrick M. McTernan, Robert W. Siggins, Anna Catinis, Angela M. Amedee, Liz Simon, Patricia E. Molina   +5 more
doaj   +1 more source

Alcohol dependence potentiates substance P/neurokinin-1 receptor signaling in the rat central nucleus of amygdala. [PDF]

, 2020
Behavioral and clinical studies suggest a critical role of substance P (SP)/neurokinin-1 receptor (NK-1R) signaling in alcohol dependence. Here, we examined regulation of GABA transmission in the medial subdivision of the central amygdala (CeM) by the SP/
Hnasko, TS, Khom, S, Roberto, M, Steinkellner, T   +3 more
core  

Collectivity of Drinking Behavior Among Adolescents: An Analysis of the Norwegian ESPAD Data 1995-2011

Nordic Studies on Alcohol and Drugs, 2014
AIMS – The aim of the current study was to test empirically two predictions from Skog’s theory of collectivity of drinking behavior, using time series data from Norwegian adolescents.
Brunborg Geir Scott, Bye Elin K., Rossow Ingeborg   +2 more
doaj   +1 more source

Naloxone’s dose-dependent displacement of [11C]carfentanil and duration of receptor occupancy in the rat brain

Scientific Reports, 2022
The continuous rise in opioid overdoses in the United States is predominantly driven by very potent synthetic opioids, mostly fentanyl and its derivatives (fentanyls).
Yeona Kang, Kelly A. O’Conor, Andrew C. Kelleher, Joseph Ramsey, Abolghasem Bakhoda, Seth M. Eisenberg, Wenjing Zhao, Tyler Stodden, Torben D. Pearson, Min Guo, Nina Brown, Jeih-San Liow, Joanna S. Fowler, Sung Won Kim, Nora D. Volkow   +14 more
doaj   +1 more source

Molecular Imaging of Opioid and Dopamine Systems: Insights Into the Pharmacogenetics of Opioid Use Disorders

Frontiers in Psychiatry, 2019
Opioid use in the United States has steadily risen since the 1990s, along with staggering increases in addiction and overdose fatalities. With this surge in prescription and illicit opioid abuse, it is paramount to understand the genetic risk factors and
Jamie A. Burns, Danielle S. Kroll, Dana E. Feldman, Christopher Kure Liu, Peter Manza, Corinde E. Wiers, Nora D. Volkow, Nora D. Volkow, Gene-Jack Wang   +8 more
doaj   +1 more source

The Relationship Between Alcohol Beverage Types and Violence [PDF]

, 2018
There is substantial evidence of an ecological association between off-premise alcohol outlets and violence. We know less, however, about how specific beverage types that are sold in the outlets might explain the difference in violence rates across ...
Snowden, Aleksandra J.
core   +1 more source

Contribution of Time of Drinking Onset and Family History of Alcohol Problems in Alcohol and Drug Use Behaviors in Argentinean College Students [PDF]

, 2013
Aims: The aim of the study was to analyze independent and potential interactive effects of age at drinking onset and family history of alcohol abuse on subsequent patterns of alcohol drinking, alcohol-related problems and substance use.
Caneto, Florencia, Garimaldi, Javier Alejandro, Pautassi, Ricardo Marcos, Pilatti, Angelina, Vera, Belén del Valle   +4 more
core   +1 more source

Acute alcohol administration dampens central extended amygdala reactivity. [PDF]

, 2018
Alcohol use is common, imposes a staggering burden on public health, and often resists treatment. The central extended amygdala (EAc)-including the bed nucleus of the stria terminalis (BST) and the central nucleus of the amygdala (Ce)-plays a key role in
Bradford, Daniel E, Curtin, John J, Fox, Andrew S, Hur, Juyoen, Kaplan, Claire M, Shackman, Alexander J, Smith, Jason F   +6 more
core   +2 more sources