Results 61 to 70 of about 14,264,243 (286)

Collaborative care for alcohol-related liver disease [PDF]

Clinical Medicine, 2007
By implementing collaborative care for patients with alcohol misuse and alcohol-related liver disease, the Royal Bolton Hospital aimed to improve and coordinate their care by recruiting a multidisciplinary team and placing the patient at the centre of all efforts.
Kieran J, Moriarty, Helen, Platt, Sandra, Crompton, Wendy, Darling, Martin, Blakemore, Sue, Hutchinson, David, Proctor, Malcolm, Brown, Burt, Burtun, George, Lipscomb, Kadukkavil, Padmakumar   +10 more
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Identifying patients at high risk of decompensated liver disease through unscheduled care attendance data: a retrospective cohort study

BMC Gastroenterology
Background Liver cirrhosis is one of the leading causes of mortality and morbidity in those of working age. Mortality from liver disease in the UK has continued to rise over the past decade.
R. Swann, J. Lewsey, D. Jamieson, S. Padmanabhan, J. P. Pell, D. Mackay, R. Dundas, J. M. Friday, T. Q. B. Tran, D. Brown, F. K. Ho, C. Hastie, M. Fleming, C. Geue, A. Stevenson, C. du Toit, A. Fraser, E. H. Forrest   +17 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Association among occupational class, alcohol consumption, and the risk of hospitalisations due to alcoholic liver diseases: a matched case-control study

BMC Public Health
Background This study aimed to identify the occupational class and specific occupations associated with hospitalisations due to alcohol-related liver disease and alcoholic liver cirrhosis, based on the distribution of alcohol consumption.
Shoko Nakazawa, Yuko Furuya, Kosuke Sakai, Kota Fukai, Kei Sano, Keika Hoshi, Noriko Kojimahara, Akihiro Toyota, Masaaki Korenaga, Masayuki Tatemichi   +9 more
doaj   +1 more source

Patients' Perspectives on Early Liver Transplantation in Alcohol‐Related Liver Disease

Hepatology Communications, 2019
Liver transplant programs in Canada require a period of 6 months of abstinence from alcohol before considering a patient with liver disease secondary to alcohol for transplantation.
Eric Wong, Paul D. Mullins, Jean‐Philippe Wallach, Eric M. Yoshida, Sigfried R. Erb, Jo‐Ann Ford, Charles H. Scudamore, Vladimir Marquez   +7 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

The relation between alcohol and cardiovascular disease in Eastern Europe: explaining the paradox. [PDF]

, 2000
BACKGROUND: Recent evidence from Eastern Europe of a positive association between alcohol and cardiovascular disease has challenged the prevailing view that drinking is cardioprotective. Consuming amounts of alcohol comparable to those consumed in France
Britton, A, McKee, M
core  

Population-based study of alcohol-related liver disease in England 2001-2018: Influence of socioeconomic position [PDF]

INTRODUCTION: England has seen an increase in deaths due to alcohol-related liver disease (ALD) since 2001. We studied the influence of socioeconomic position on the incidence of ALD and the mortality after ALD diagnosis in England in 2001–2018.METHODS ...
Crooks, Colin, Kann, Anna Emilie, Card, Tim, Jepsen, Peter, Morling, Joanne, Kraglund, Frederik, Askgaard, Gro, Jensen, Morten Daniel, West, Joe   +8 more
core   +1 more source