Results 31 to 40 of about 1,516,378 (315)
Sex differences in nicotine-enhanced Pavlovian conditioned approach in rats
Biology of Sex Differences, 2019 Background Nicotine exposure enhances Pavlovian conditioned approach (PCA), or the learned approach to reward-predictive cues. While females show elevated approach to conditioned stimuli compared to males, potentially indicating heightened addiction ...
Sierra J. Stringfield +3 more
doaj +1 more source
Investigating Interactions of Biomembranes and Alcohols: A Multiscale Approach [PDF]
, 2004 We study the interaction of lipid bilayers with short chain alcohols using molecular dynamics on different length scales. We use detailed atomistic modeling and modeling on the length scale where an alcohol is just an amphiphilic dimer. Our strategy is to calibrate a coarse--grained model against the detailed model at selected state points at low ...
arxiv +1 more source
Python (deep learning and machine learning) for EEG signal processing on the example of recognizing the disease of alcoholism [PDF]
, 2020 Alcoholism is one of the most common diseases in the world. This type of substance abuse leads to mental and physical dependence on ethanol-containing drinks. Alcoholism is accompanied by progressive degradation of the personality and damage to the internal organs. Today still not exists a quick diagnosis method to detect this disease.
arxiv +1 more source
Frontiers in Psychiatry, 2019 Opioid use in the United States has steadily risen since the 1990s, along with staggering increases in addiction and overdose fatalities. With this surge in prescription and illicit opioid abuse, it is paramount to understand the genetic risk factors and
Jamie A. Burns +8 more
doaj +1 more source
Non-rotational mechanism of polarization in alcohols [PDF]
The Journal of Physical Chemistry B vol. 124, 11022 (2020), 2020 Chemical polarity governs various mechanical, chemical and thermodynamic properties of dielectrics. Polar liquids have been amply studied, yet the basic mechanisms underpinning their dielectric properties remain not fully understood, as standard models following Debye's phenomenological approach do not account for quantum effects and cannot aptly ...
arxiv +1 more source
Nordic Studies on Alcohol and Drugs, 2014 AIMS – The aim of the current study was to test empirically two predictions from Skog’s theory of collectivity of drinking behavior, using time series data from Norwegian adolescents.
Brunborg Geir Scott +2 more
doaj +1 more source
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Addiction Science & Clinical Practice, 2022 Background Opioid use disorder (OUD) is a serious health condition that is effectively treated with buprenorphine. However, only a minority of people with OUD are able to access buprenorphine.
Caleb J. Banta-Green +6 more
doaj +1 more source