Results 31 to 40 of about 3,846,885 (313)

Sex differences in nicotine-enhanced Pavlovian conditioned approach in rats

Biology of Sex Differences, 2019
Background Nicotine exposure enhances Pavlovian conditioned approach (PCA), or the learned approach to reward-predictive cues. While females show elevated approach to conditioned stimuli compared to males, potentially indicating heightened addiction ...
Sierra J. Stringfield, Aric C. Madayag, Charlotte A. Boettiger, Donita L. Robinson   +3 more
doaj   +1 more source

The Community-Based Medication-First program for opioid use disorder: a hybrid implementation study protocol of a rapid access to buprenorphine program in Washington State

Addiction Science & Clinical Practice, 2022
Background Opioid use disorder (OUD) is a serious health condition that is effectively treated with buprenorphine. However, only a minority of people with OUD are able to access buprenorphine.
Caleb J. Banta-Green, Mandy D. Owens, Jason R. Williams, Jeanne M. Sears, Anthony S. Floyd, Wendy Williams-Gilbert, Susan Kingston   +6 more
doaj   +1 more source

Alcohol use, alcohol-related aggression and intimate partner abuse: a cross-sectional survey of convicted versus general population men in Scotland [PDF]

, 2017
Introduction and Aims. Scotland has a particular problem with alcohol, and the links between intimate partner abuse (IPA) and alcohol appear stronger here than elsewhere across Europe.
Forsyth, Alasdair, Gilchrist, Elizabeth, Godwin, Jon, Ireland, Lana, Laxton, Tim   +4 more
core   +1 more source

Preliminary support for the role of alcohol cues in food cravings and attentional biases [PDF]

, 2019
This study examined whether alcohol odors, in isolation or when combined with pictures, would influence food attentional biases and cravings. Participants' cravings and attentional biases to food and alcohol pictures were assessed after exposure to ...
Cyders, Melissa A., Karyadi, Kenny A.
core   +1 more source

Collectivity of Drinking Behavior Among Adolescents: An Analysis of the Norwegian ESPAD Data 1995-2011

Nordic Studies on Alcohol and Drugs, 2014
AIMS – The aim of the current study was to test empirically two predictions from Skog’s theory of collectivity of drinking behavior, using time series data from Norwegian adolescents.
Brunborg Geir Scott, Bye Elin K., Rossow Ingeborg   +2 more
doaj   +1 more source

Time-varying SUVr reflects the dynamics of dopamine increases during methylphenidate challenges in humans

Communications Biology, 2023
Combined PET imaging and mathematical simulations reveal that the rate of dopamine increase in the striatum underlies self-reports of drug “high” in response to oral and intravenous methylphenidate challenges in ...
Dardo Tomasi, Peter Manza, Jean Logan, Ehsan Shokri-Kojori, Michele-Vera Yonga, Danielle Kroll, Dana Feldman, Katherine McPherson, Catherine Biesecker, Evan Dennis, Allison Johnson, Kai Yuan, Wen-Tung Wang, John A. Butman, Gene-Jack Wang, Nora D. Volkow   +15 more
doaj   +1 more source

Chronic Binge Alcohol and Ovarian Hormone Loss Dysregulate Circulating Immune Cell SIV Co-Receptor Expression and Mitochondrial Homeostasis in SIV-Infected Rhesus Macaques

Biomolecules, 2022
Effective antiretroviral therapy (ART) has transitioned HIV to a chronic disease, with more than 50% of people living with HIV (PLWH) being over the age of 50.
Patrick M. McTernan, Robert W. Siggins, Anna Catinis, Angela M. Amedee, Liz Simon, Patricia E. Molina   +5 more
doaj   +1 more source

Is alcohol dependence best viewed as a chronic relapsing disorder? [PDF]

, 2011
This 'For Debate' paper starts by recognizing the growing trend towards considering alcohol dependence as a chronic relapsing disorder. We argue that the adoption of this model results from focusing on those in treatment for alcohol dependence rather ...
American Psychiatric Association, Andreasson, Babor, Babor, Breese, Cacciola, Caetano, Cartwright, Chan, Cohen, Cunningham, Cunningham, Cunningham, Dawson, Dawson, Dawson, Dawson, de Bruijn, Ducci, Edwards, Edwards, Edwards, Edwards, Enoch, Fillmore, Finney, Gorman, Grant, Heather, Hingson, Institute of Medicine, Jacob, Kalant, Klingemann, Ko, Koob, Kreitman, Leake, Leshner, Linke, McAweeney, McCambridge, McKay, McKay, McLellan, McLellan, McLellan, McLellan, McLellan, Merline, Midanik, Miller, Miller, Miller, Miller, Moss, O'Brien, Orford, Penick, Prochaska, Room, Room, Rose, Rosenthal, Rosenthal, Saitz, Schuckit, Schuckit, Scott, Stockwell, Timko, Tucker, Vaillant, Volkow, Weisner, Weisner, Weisner, Willenbring, World Health Organization, Wrase   +79 more
core   +2 more sources

Molecular Imaging of Opioid and Dopamine Systems: Insights Into the Pharmacogenetics of Opioid Use Disorders

Frontiers in Psychiatry, 2019
Opioid use in the United States has steadily risen since the 1990s, along with staggering increases in addiction and overdose fatalities. With this surge in prescription and illicit opioid abuse, it is paramount to understand the genetic risk factors and
Jamie A. Burns, Danielle S. Kroll, Dana E. Feldman, Christopher Kure Liu, Peter Manza, Corinde E. Wiers, Nora D. Volkow, Nora D. Volkow, Gene-Jack Wang   +8 more
doaj   +1 more source

Naloxone’s dose-dependent displacement of [11C]carfentanil and duration of receptor occupancy in the rat brain

Scientific Reports, 2022
The continuous rise in opioid overdoses in the United States is predominantly driven by very potent synthetic opioids, mostly fentanyl and its derivatives (fentanyls).
Yeona Kang, Kelly A. O’Conor, Andrew C. Kelleher, Joseph Ramsey, Abolghasem Bakhoda, Seth M. Eisenberg, Wenjing Zhao, Tyler Stodden, Torben D. Pearson, Min Guo, Nina Brown, Jeih-San Liow, Joanna S. Fowler, Sung Won Kim, Nora D. Volkow   +14 more
doaj   +1 more source