BMJ, 1982 Abstract There is evidence for a dose-response relationship between alcohol consumption and risk of liver cirrhosis, cancers of the oropharynx, larynx, oesophagus, rectum (beer only), liver, and female breast, and violent death, but the relationship between alcohol consumption and cardiovascular disease is more complex.
openaire +2 more sources
Molecular Genetic Influences on Normative and Problematic Alcohol Use in a Population-Based Sample of College Students [PDF]
, 2017 Background: Genetic factors impact alcohol use behaviors and these factors may become increasingly evident during emerging adulthood. Examination of the effects of individual variants as well as aggregate genetic variation can clarify mechanisms ...
Adkins, Amy +16 more
core +2 more sources
4191 The Role of Suggestibility and Trait Anxiety in Young Adult Alcohol Use
Journal of Clinical and Translational Science, 2020 OBJECTIVES/GOALS: The purpose of this study was to investigate how suggestibility and social susceptibility relate to alcohol use in young adult non-dependent alcohol users, and the role of trait anxiety in this relationship. We hypothesized that greater
Alexandra Cowand +6 more
doaj +1 more source
Cholesterol as a modulator of cannabinoid receptor CB2 signaling
Scientific Reports, 2021 Signaling through integral membrane G protein-coupled receptors (GPCRs) is influenced by lipid composition of cell membranes. By using novel high affinity ligands of human cannabinoid receptor CB2, we demonstrate that cholesterol increases basal ...
Alexei Yeliseev +7 more
doaj +1 more source
Global statistics on alcohol, tobacco and illicit drug use: 2017 status report
Addiction, 2018 AIMS This review provides an up-to-date curated source of information on alcohol, tobacco and illicit drug use and their associated mortality and burden of disease.
A. Peacock +16 more
semanticscholar +1 more source
cAMP Signaling in Pathobiology of Alcohol Associated Liver Disease
Biomolecules, 2020 The importance of cyclic adenosine monophosphate (cAMP) in cellular responses to extracellular signals is well established. Many years after discovery, our understanding of the intricacy of cAMP signaling has improved dramatically.
Mohamed Elnagdy +3 more
doaj +1 more source
Prevalence of Fetal Alcohol Spectrum Disorders in 4 US Communities
Journal of the American Medical Association (JAMA), 2018 Importance Fetal alcohol spectrum disorders are costly, life-long disabilities. Older data suggested the prevalence of the disorder in the United States was 10 per 1000 children; however, there are few current estimates based on larger, diverse US ...
Philip A. May +28 more
semanticscholar +1 more source
Alcohol use, alcohol-related aggression and intimate partner abuse: a cross-sectional survey of convicted versus general population men in Scotland [PDF]
, 2017 Introduction and Aims. Scotland has a particular problem with alcohol, and the links between intimate partner abuse (IPA) and alcohol appear stronger here than elsewhere across Europe.
Forsyth, Alasdair +4 more
core +1 more source
Sex differences in nicotine-enhanced Pavlovian conditioned approach in rats
Biology of Sex Differences, 2019 Background Nicotine exposure enhances Pavlovian conditioned approach (PCA), or the learned approach to reward-predictive cues. While females show elevated approach to conditioned stimuli compared to males, potentially indicating heightened addiction ...
Sierra J. Stringfield +3 more
doaj +1 more source
Alcohol consumption among Chilean adolescents: examining individual, peer, parenting and environmental factors [PDF]
, 2013 AIMS: This study examined whether adolescents from Santiago, Chile who had never drunk alcohol differed from those who had drunk alcohol but who had never experienced an alcohol-related problem, as well as from those who had drunk and who had experienced
Bares, Cristina +3 more
core +1 more source