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Anticonvulsants for alcohol dependence

Cochrane Database of Systematic Reviews, 2010
Alcohol dependence is a major public health problem that is characterised by recidivism and a host of medical and psychosocial complications. Besides psychosocial interventions, different pharmacological interventions have been or currently are under investigation through Cochrane systematic reviews.The primary aim of the review is to assess the ...
Emanuela Trogu   +3 more
openaire   +3 more sources

The Diagnosis of Alcohol and Cannabis Dependence in Cocaine Dependents and Alcohol Dependence in their Families

British Journal of Addiction, 1989
SummaryGenetic research in alcoholism has made major advances in recent decades. Twin, adoption, high‐risk and familial studies have demonstrated an inheritance factor in alcoholism. Few studies have demonstrated a genetic predisposition to cocaine and cannabis dependence.
Beth M. Belkin   +3 more
openaire   +2 more sources

The Genetics of Alcohol Intake and of Alcohol Dependence

Alcoholism: Clinical and Experimental Research, 2004
Background: Because alcohol has multiple dose‐dependent consequences, it is important to understand the causes of individual variation in the amount of alcohol used. The aims of this study were to assess the long‐term repeatability and genetic or environmental causes of variation in alcohol intake and to estimate the degree of overlap with causes of ...
Nicholas G. Martin   +6 more
openaire   +4 more sources

Pharmacotherapy of alcohol dependence

Trends in Pharmacological Sciences, 1997
The current pharmacotherapeutic approaches to alcohol dependence, together with the results of a number of clinical trials, are reviewed in this article. Despite the somewhat disappointing clinical results, pharmacotherapeutic interventions did lead to some small, but significant, improvements in alcohol abstinence rates.
Gerald Zernig, Hans Fabisch, K. Fabisch
openaire   +3 more sources

Topiramate for Alcohol Dependence

Annals of Pharmacotherapy, 2008
Objective: To evaluate the evidence for the use of topiramate for alcohol dependence. Data Sources: MEDLINE (l 966-June 2008) and Cochrane Database (2008, Issue 1) searches were conducted using the search terms alcohol dependence and topiramate. Bibliographies of selected articles were examined for additional data sources.
Christina L Olmsted, Denise R Kockler
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Alcohol, Alcoholism, and the Problem of Dependence

1977
Investigators of sleep physiology and of alcoholism have several common interests. Ethanol ingestion affects EEG sleep stages. It may also modify the metabolism of the biogenic amines, which are thought to play an important role in the regulation of sleep (see Chapters 1 and 2).
Richard Jed Wyatt   +2 more
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The genetics of alcohol dependence

Annals of the New York Academy of Sciences, 2012
Alcohol consumption dates back to the Neolithic period, and alcohol dependence contributes substantially to the current global burden of disease. Despite this, optimal therapies and preventive strategies are lacking. Formal genetic studies of alcohol dependence have shown that genetic factors play as large a role in disease etiology as environmental ...
Jens Treutlein, Marcella Rietschel
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The genetics of alcohol dependence

Current Psychiatry Reports, 2006
Alcohol dependence is a common, complex disorder, which affects millions of people worldwide and causes considerable burden in terms of interpersonal and societal costs. Family, twin, and adoption studies have convincingly demonstrated that genes play an important role in the development of alcohol dependence, with heritability estimates in the range ...
Danielle M. Dick, Laura J. Bierut
openaire   +3 more sources

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