Results 71 to 80 of about 552,839 (349)

Genetics of alcohol dependence [PDF]

open access: yesPsychiatry and Clinical Neurosciences, 2011
Twin, family, and adoption studies have consistently shown that genetic factors play an important role in the pathogenesis of alcohol dependence. Numerous studies have aimed to identify genes that contribute to susceptibility to alcohol dependence. Whole‐genome linkage studies have identified several chromosomal regions that are linked with alcohol ...
Mitsuru, Kimura, Susumu, Higuchi
openaire   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

A Long-Term Study of Sons of Alcoholics. [PDF]

open access: yes, 1995
Men with a family history of alcoholism appear to have a lower intensity reaction to alcohol's effects than those without this family history. This study investigated whether a lower reaction could encourage greater alcohol consumption among family ...
Schuckit, Marc A
core  

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Relationship of attention-deficit/hyperactivity disorder symptom severity with severity of alcohol-related problems in a sample of inpatients with alcohol use disorder

open access: yesNeuropsychiatric Disease and Treatment, 2016
Muge Bozkurt,1 Cuneyt Evren,1 Gokhan Umut,1 Bilge Evren2 1Research, Treatment and Training Center for Alcohol and Substance Dependence, Bakirkoy Prof Dr Mazhar Osman Training and Research Hospital for Psychiatry ...
Bozkurt M, Evren C, Umut G, Evren B
doaj  

Study of prevalence of Sexual dysfunction in Alcohol Dependant individuals: A cross sectional study [PDF]

open access: yesPerspectives In Medical Research, 2017
Background: The chances of developing sexual dysfunctions appear to increase with increasing years of alcohol consumed. Various explanations have been offered for sexual dysfunction in alcoholic patients.
Pavan Kumar K1 , Apurva Chada2 , Ravinder Anaveni3 , Sinjoni Roy4
doaj  

Wareniklina – częściowy agonista receptorów nikotynowych w terapii zespołu uzależnienia od alkoholu

open access: yesAlcoholism and Drug Addiction, 2016
The pharmacotherapy currently used for alcohol dependence may reduce alcohol consumption and extend abstinence periods. However, it is effective in only about 30% of addicted subjects.
Natalia Obsada   +1 more
doaj   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Drinking pattern in persons with alcohol dependence with and without cirrhosis: A hospital-based comparative study

open access: yesIndian Journal of Psychiatry, 2018
Background: Worldwide, alcohol is the most frequently used and socially accepted hepatotoxin. However, not everyone who has alcohol dependence develops alcoholic cirrhosis, and does quantity/type or pattern of alcohol intake determine the development of ...
Anil Kakunje   +5 more
doaj   +1 more source

Alcohol dependence potentiates substance P/neurokinin-1 receptor signaling in the rat central nucleus of amygdala. [PDF]

open access: yes, 2020
Behavioral and clinical studies suggest a critical role of substance P (SP)/neurokinin-1 receptor (NK-1R) signaling in alcohol dependence. Here, we examined regulation of GABA transmission in the medial subdivision of the central amygdala (CeM) by the SP/
Hnasko, TS   +3 more
core  

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