Results 71 to 80 of about 1,742,228 (306)

Wareniklina – częściowy agonista receptorów nikotynowych w terapii zespołu uzależnienia od alkoholu

Alcoholism and Drug Addiction, 2016
The pharmacotherapy currently used for alcohol dependence may reduce alcohol consumption and extend abstinence periods. However, it is effective in only about 30% of addicted subjects.
Natalia Obsada, Jadwiga Zalewska-Kaszubska   +1 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Relationship of attention-deficit/hyperactivity disorder symptom severity with severity of alcohol-related problems in a sample of inpatients with alcohol use disorder

Neuropsychiatric Disease and Treatment, 2016
Muge Bozkurt,1 Cuneyt Evren,1 Gokhan Umut,1 Bilge Evren2 1Research, Treatment and Training Center for Alcohol and Substance Dependence, Bakirkoy Prof Dr Mazhar Osman Training and Research Hospital for Psychiatry ...
Bozkurt M, Evren C, Umut G, Evren B
doaj  

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Drinking pattern in persons with alcohol dependence with and without cirrhosis: A hospital-based comparative study

Indian Journal of Psychiatry, 2018
Background: Worldwide, alcohol is the most frequently used and socially accepted hepatotoxin. However, not everyone who has alcohol dependence develops alcoholic cirrhosis, and does quantity/type or pattern of alcohol intake determine the development of ...
Anil Kakunje, Haridas Kanaradi, Ganesh Pai, Ravichandra Karkal, Dilshana Nafisa, Premchand Chandrasekaran   +5 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Study of prevalence of Sexual dysfunction in Alcohol Dependant individuals: A cross sectional study [PDF]

Perspectives In Medical Research, 2017
Background: The chances of developing sexual dysfunctions appear to increase with increasing years of alcohol consumed. Various explanations have been offered for sexual dysfunction in alcoholic patients.
Pavan Kumar K1 , Apurva Chada2 , Ravinder Anaveni3 , Sinjoni Roy4
doaj  

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Alcohol expectencies and treatment: a review of the literature [PDF]

, 2000
Plan BThis paper reviews the main issues in alcohol expectancy research, and identifies how these findings can best be used in substance abuse treatment.
Balow, Jane L.
core  

Efficacy and safety of pregabalin in alcohol dependence

, 2008
INTRODUCTION: Pregabalin is a new anxiolytic that selectively binds to the alpha2-delta subunit of voltage-gated calcium channels, inhibiting release of excessive levels of excitatory neurotransmitters. In this open-label trial we aimed to investigate
Mazza, Marianna, Bria, Pietro, Tedeschi, Daniela, Martinotti, Giovanni, Di Nicola, Marco, Janiri, Luigi   +5 more
core   +1 more source