Results 101 to 110 of about 650,959 (208)

Crowder‐specific modulation of hepatitis C virus NS3/4A protease activity and local structural dynamics

open access: yesProtein Science, Volume 35, Issue 11, November 2026.
Abstract Macromolecular crowding modulates enzyme behavior in crowder‐ and protein‐specific ways, yet its impact on viral proteases, which are often key therapeutic targets, remains unclear. Here, we investigated the hepatitis C virus NS3/4A protease under increasing concentrations of polyethylene glycols (PEGs), ficoll, dextran, and lysozyme using ...
Małgorzata Lobka, Joanna Trylska
wiley   +1 more source

Alcohol and complex society

open access: yes, 1945
Chapter in the volume entitled "Alcohol, science and society. Twenty-nine lectures with discussions as given at the Yale Summer School of Alcohol Studies.

core   +1 more source

Beyond monofunctionality: structural perspectives on phenol oxidase side activity in a catalase

open access: yesActa Crystallographica Section D, Volume 82, Issue 11, Page 1224-1239, November 2026.
Structural and biochemical characterization of the extracellular fungal catalase ClCPO uncovers an unexpected phenol oxidase promiscuity. Crystal structures, substrate docking and electron‐transfer pathway analysis identify ligand‐binding regions and support a working mechanistic model for catalase‐associated phenol oxidase activity.Catalases are ...
Christina Ferousi   +5 more
wiley   +1 more source

The problems of alcohol

open access: yes, 1945
Chapter in the volume entitled "Alcohol, science and society. Twenty-nine lectures with discussions as given at the Yale Summer School of Alcohol Studies.

core   +1 more source

Unravelling the Chemolithoautotrophic Metabolism of the Carboxydotrophic Knallgas Bacterium Hydrogenophaga pseudoflava

open access: yesMicrobial Biotechnology, Volume 19, Issue 11, November 2026.
Proteomics of the aerobic carboxydotroph Hydrogenophaga pseudoflava across trophic conditions revealed that an unphysiological CO concentration causes a redox imbalance and stress response. CO dehydrogenase I and the membrane‐bound hydrogenase were essential for CO and H2 oxidation, respectively, whereas the soluble hydrogenase likely supports redox ...
Simon Grieshaber   +8 more
wiley   +1 more source

Alcohol Bibliography Series: Recent Topics in Alcohol Studies, Rutgers University

open access: yes, 1998
A sample order form dated from the end of 1990s to request specialized bibliographies on alcohol ...

core   +1 more source

DBT Modulates Copper‐Dependent Cuproptosis‐Related Injury in Experimental Alcoholic Cardiomyopathy

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Alcoholic cardiomyopathy (ACM) is a severe cardiovascular complication of chronic alcohol consumption, but its underlying mechanisms remain incompletely understood. Cuproptosis is a recently identified copper‐dependent form of regulated cell death; however, its role in ACM remains unclear.
Zhihao Pan   +3 more
wiley   +1 more source

In memoriam: Vera Efron (1905-1993)

open access: yes, 1993
Obituary of Vera Efron written by Mar Keller for the Journal of Studies on ...
Keller, Mark
core   +1 more source

WTAP‐mediated m6A RNA methylation promotes diabetic foot ulcer healing under negative pressure wound therapy

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 11, Page 2019-2033, November 2026.
NPWT significantly increases the suppressed WTAP and m6A levels in DFU patients, correlating directly with better 4‐week healing outcomes. In vitro, negative pressure reverses high‐glucose‐induced WTAP downregulation, restoring the cell proliferation and migration necessary for wound repair.
Yutong Li   +6 more
wiley   +1 more source

Yale Reports (from WTIC - 1080): Alcohol and the Citizen

open access: yes, 1959
Copy of the transcript of the radio program Yale Reports, which hosted a series entitled "Alcohol and the Citizen" from September 20 to October 18, 1959 about the Center of Alcohol Studies. Editor Edith Kerr talked with several CAS faculty members.

core   +1 more source

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