GDNF and alcohol use disorder [PDF]
AbstractGlial cell line‐derived neurotrophic factor (GDNF) has been extensively studied for its role in the development and maintenance of the midbrain dopaminergic system, although evidence suggests that GDNF also plays a role in drug and alcohol addiction. This review focuses on the unique actions of GDNF in the mechanisms that prevent the transition
Segev Barak+3 more
openaire +4 more sources
Practical outpatient pharmacotherapy for alcohol use disorder
Alcohol use disorder (AUD) is commonly encountered in clinical practice. A combination of psychosocial intervention and pharmacotherapy is the cornerstone of AUD treatment.
Youngjung Kim+3 more
doaj +1 more source
Alcohol Use and Misuse Among Chinese Psychiatrists During the Early COVID-19 Pandemic
AimSurvey alcohol use and misuse among Chinese psychiatrists during the Coronavirus diseases 2019 (COVID-19) pandemic.MethodsWe conducted a large-scale, nationwide online survey of psychiatrists regarding their alcohol use during the pandemic.
Daming Mo+16 more
doaj +1 more source
The role of alcohol response phenotypes in the risk for alcohol use disorder [PDF]
Heavy alcohol use is pervasive and one of our most significant global health burdens. Early theories posited that certain alcohol response phenotypes, notably low sensitivity to alcohol (‘low-level response’) imparts risk for alcohol use disorder (AUD ...
Cao, Dingcai+4 more
core +1 more source
Substance use disorders in adolescents with attention deficit hyperactivity disorder: a 4-year follow-up study [PDF]
Aim To examine the relationship between a childhood diagnosis of attention deficit hyperactivity disorder (ADHD) with or without oppositional defiant disorder (ODD)/conduct disorder (CD) and the development of later alcohol/drug use disorder ...
Buitelaar, JK+8 more
core +3 more sources
Use of Gabapentin in the Treatment of Substance Use and Psychiatric Disorders: A Systematic Review
Objective: Gabapentin (GBP) is an anticonvulsant medication that is also used to treat restless legs syndrome (RLS) and posttherapeutic neuralgia. GBP is commonly prescribed off-label for psychiatric disorders despite the lack of strong evidence. However,
Saeed Ahmed+10 more
doaj +1 more source
Alcohol causes end-organ damage in drinkers, and alcohol dependence is associated with poor self-care, complicating chronic disease management. A drinking history and index of suspicion for alcohol misuse is part of comprehensive medical assessment. Identification of hazardous and harmful drinking, and provision of brief advice and/or referral, should ...
openaire +1 more source
Prevalence and patterns of hazardous and harmful alcohol consumption assessed using the AUDIT among Bhutanese refugees in Nepal. [PDF]
AIMS: This study sought to ascertain the prevalence of hazardous and harmful alcohol consumption among Bhutanese refugees in Nepal and to identify predictors of elevated risk in order to better understand intervention need. METHODS: Hazardous and harmful
Jordans, Mark+4 more
core +2 more sources
Alcohol Use Disorder: Neurobiology and Therapeutics
Alcohol use disorder (AUD) encompasses the dysregulation of multiple brain circuits involved in executive function leading to excessive consumption of alcohol, despite negative health and social consequences and feelings of withdrawal when access to ...
Waisley Yang+4 more
doaj +1 more source
A systematic review of physical activity correlates in alcohol use disorders [PDF]
Background: Physical activity might promote mental and physical health in persons with alcohol use disorder. Understanding the barriers and facilitators of participation in physical activity in persons with alcohol use disorder is an essential first ...
Amber De Herdt+37 more
core +2 more sources