Results 21 to 30 of about 279,479 (299)

RNA biomarkers for alcohol use disorder

open access: yesFrontiers in Molecular Neuroscience, 2022
Alcohol use disorder (AUD) is highly prevalent and one of the leading causes of disability in the US and around the world. There are some molecular biomarkers of heavy alcohol use and liver damage which can suggest AUD, but these are lacking in ...
Laura B. Ferguson   +7 more
doaj   +1 more source

The Alcohol Use Disorders Identification Test (AUDIT) in the Russian language - a systematic review of validation efforts and application challenges

open access: yesSubstance Abuse Treatment, Prevention, and Policy, 2021
The Alcohol Use Disorders Identification Test (AUDIT) is one of the most frequently used screening instrument for hazardous and harmful use of alcohol and potential alcohol dependence in primary health care (PHC) and other settings worldwide. It has been
Maria Neufeld   +14 more
doaj   +1 more source

Alcohol Misuse and Alcohol Use Disorder in Adolescents

open access: yesAddicta: The Turkish Journal on Addictions
Adolescence is a distinct developmental stage marked by increased levels of novelty-seeking, reward sensitiv- ity, and risk-taking behaviors, which often heighten the risk for alcohol use.
İpek Süzer Gamlı, Mehmet Can Erata
doaj   +1 more source

Alcohol Use Disorder: Neurobiology and Therapeutics

open access: yesBiomedicines, 2022
Alcohol use disorder (AUD) encompasses the dysregulation of multiple brain circuits involved in executive function leading to excessive consumption of alcohol, despite negative health and social consequences and feelings of withdrawal when access to ...
Waisley Yang   +4 more
doaj   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou   +10 more
wiley   +1 more source

Alcohol Use and Misuse Among Chinese Psychiatrists During the Early COVID-19 Pandemic

open access: yesFrontiers in Psychiatry, 2022
AimSurvey alcohol use and misuse among Chinese psychiatrists during the Coronavirus diseases 2019 (COVID-19) pandemic.MethodsWe conducted a large-scale, nationwide online survey of psychiatrists regarding their alcohol use during the pandemic.
Daming Mo   +16 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Patterns of Alcohol Use and Alcohol Use Disorders and Their Sociodemographic Correlates: Findings from a Cross sectional Study among Male Patients Attending a NIA Outpatient Department

open access: yesJournal of Ayurveda
Introduction: Alcohol consumption is a significant public health issue, contributing to substantial morbidity and mortality worldwide. In India, alcohol use prevalence ranges from 3.8% to 21%, predominantly affecting men. Despite estimates of alcohol use
Viadya Amol S. Kadu   +3 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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