Results 41 to 50 of about 301,940 (306)

Risk factors for incidence and persistence of disability in chronic major depression and alcohol use disorders: longitudinal analyses of a population-based study [PDF]

, 2014
BackgroundMajor depression and alcohol use disorders are risk factors for incidence of disability. However, it is still unclear whether a chronic course of these health conditions is also prospectively associated with incidence of disability.
José Luis Ayuso-Mateos, Ayuso-Mateos, J., Cieza, A., Alarcos Cieza, Chatterji, S., Cabello, M., Caballero, F., Somnath Chatterji, María Cabello, Francisco Félix Caballero   +9 more
core   +1 more source

RNA biomarkers for alcohol use disorder

Frontiers in Molecular Neuroscience, 2022
Alcohol use disorder (AUD) is highly prevalent and one of the leading causes of disability in the US and around the world. There are some molecular biomarkers of heavy alcohol use and liver damage which can suggest AUD, but these are lacking in ...
Laura B. Ferguson, Laura B. Ferguson, Laura B. Ferguson, R. Dayne Mayfield, R. Dayne Mayfield, Robert O. Messing, Robert O. Messing, Robert O. Messing   +7 more
doaj   +1 more source

Alcohol Misuse and Alcohol Use Disorder in Adolescents

Addicta: The Turkish Journal on Addictions
Adolescence is a distinct developmental stage marked by increased levels of novelty-seeking, reward sensitiv- ity, and risk-taking behaviors, which often heighten the risk for alcohol use.
İpek Süzer Gamlı, Mehmet Can Erata
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Factsheet: Alcohol, crime and disorder in the night-time economy [PDF]

, 2010
The rapid expansion in recent years of the night-time economy (NTE) - now an important part of the leisure, tourism and service industries - raises serious crime and public health ...
Alcohol Concern, Newton, Andrew D., Hadfield, Phil   +2 more
core  

Animal Models Used to Study Alcohol Use Disorder [PDF]

, 2023
For ethical and technical reasons, research in humans has some limitations and requires the support of animal models. Numerous animal models have been developed over the years to study alcohol consumption and model alcohol-related behaviors in several ...
Coppola, Andrea,, Augier, Eric,, Lguensat, Asmae,   +2 more
core   +1 more source

Alcohol use disorder and its determinant factors among patients with schizophrenia attending treatment at mental specialized hospital, Addis Ababa, Ethiopia: A cross-sectional study

SAGE Open Medicine, 2021
Background: Alcohol use disorder is one of the primary causes of avoidable death, illness, and injury in many societies throughout the world. Although alcohol use disorder can influence the natural history of a disease, disease recurrence, quality of ...
Habtamu Tadesse, Yohannes Mirkena Lemu, Tadesse Misgana   +2 more
doaj   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Lifetime affective and alcohol use disorder: impact of comorbidity on current functioning and service use in a rural population [PDF]

, 2014
Background: Depression and alcohol use problems frequently co-occur and significant barriers to service use for co-morbid mental health problems exist.
Lewin, TJ, Yong, YM, Kelly, BJ, Kay-Lambkin, FJ, Inder, KJ, Handley T E, Handley, Tonelle   +6 more
core   +2 more sources