Results 71 to 80 of about 2,165,233 (395)
The Pharmacogenetics of Alcohol Use Disorder [PDF]
Alcoholism: Clinical and Experimental Research, 2015 Annually, the use and abuse of alcohol contributes to millions of deaths and billions of dollars in societal costs. To determine the impact of genetic variation on the susceptibility to the disorder and its response to treatment, studies have been conducted to assess the contribution of a variety of candidate genetic variants.
Henry R. Kranzler +2 more
openaire +3 more sources
Treatment Interventions for Women With Alcohol Use Disorder
Alcohol research : current reviews, 2020 Women with alcohol use disorder (AUD) experience more barriers to AUD treatment and are less likely to access treatment than men with AUD. A literature review identified several barriers to women seeking help: low perception of a need for treatment ...
B. McCrady, E. Epstein, Kathryn F. Fokas
semanticscholar +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Alcohol Use In Mexican-Americans By Nativity: The Role Of Ethnic Identity, Acculturation, And Acculturative Stress [PDF]
, 2013 The present study examined alcohol use disorder symptoms among Mexican-Americans. Participants consisted of a community-based sample of 237 Mexican-American adults living in the Midwest United States. The role of nativity status and cultural variables in
Vallejo, Leticia G.
core +1 more source
Heliyon, 2022 The COVID-19 pandemic and its societal impact may cause long-term behavioral changes in alcohol use due to increased psychological distress, unemployment, and time spent home.
Mitchell J. Andersson, Anders Håkansson
doaj
Gabapentin for alcohol use disorder
Canadian Family Physician, 2021 Is gabapentin an effective treatment for alcohol use disorder (AUD)? Gabapentin treatment avoided more heavy drinking days (> 5 standard drinks/day) than placebo (27% vs 9%). Gabapentin can be a second-line, off-label option to treat AUD. However, there is mixed evidence and concerns about abuse-
Christina Korownyk +2 more
openaire +3 more sources
Current Directions in Psychological Science, 2020 The context in which drinking occurs is a critical but relatively understudied factor in alcohol use disorder (AUD) etiology. In this article, I offer a social-contextual framework for examining AUD risk by reviewing studies on the unique antecedents and
Kasey G. Creswell
semanticscholar +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
GABAB receptor ligands for the treatment of alcohol use disorder: preclinical and clinical evidence. [PDF]
, 2014 The present paper summarizes the preclinical and clinical studies conducted to define the "anti-alcohol" pharmacological profile of the prototypic GABAB receptor agonist, baclofen, and its therapeutic potential for treatment of alcohol use disorder (AUD).
Agabio R, Colombo G
core +2 more sources
Journal of Clinical Medicine, 2020 Macronutrients and trace elements are important components of living tissues that have different metabolic properties and functions. Trace elements participate in the regulation of immunity through humoral and cellular mechanisms, nerve conduction ...
J. Baj +7 more
semanticscholar +1 more source