Results 71 to 80 of about 868,733 (270)

Alcohol Biomarker Phosphatidylethanol as a Predictor of the Severity of Alcohol Withdrawal Syndrome.

, 2023
AIMS to investigate the relationship between phosphatidylethanol (PEth) and withdrawal severity in patients with alcohol use disorder (AUD). METHODS in 34 patients with AUD admitted for treatment of acute alcohol withdrawal, data were available ...
Novak, Lan, Bünter, Adina, Weinmann, Wolfgang, Stöth, Frederike, Wopfner, Alexander, Pfeifer, Philippe, Soravia, Leila M   +6 more
core   +1 more source

A Seizure Attributed to Ofloxacine in a Woman Undergoing Detoxification for Alcohol Dependence

Case Reports in Medicine, 2009
Objective. To report one case of seizure following administration of ofloxacin. Case Summary. A 38-year-old woman with alcohol dependence but no prior history of seizure disorder admitted in our inpatient alcohol detoxification program was prescribed ...
Pierre Lahmek, Laurent Michel, Nadine Meunier, Henri-Jean Aubin   +3 more
doaj   +1 more source

How to Manage Self-Poisoning With Baclofen in Alcohol Use Disorder? Current Updates

Frontiers in Psychiatry, 2018
Specialists in addiction medicine continue to debate whether baclofen is still indicated to treat alcohol use disorders in view of conflicting results as to its efficacy.
Nicolas Franchitto, Nicolas Franchitto, Nicolas Franchitto, Benjamin Rolland, Benjamin Rolland, Fanny Pelissier, Nicolas Simon   +6 more
doaj   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Studies of Alcohol: Past, Present and Future

, 1989
Copy of the article Mendelson, J. H., & Mello, N. K. (1989). Studies of Alcohol: Past, Present and Future. Journal of Studies on Alcohol, 50(4), 293–196.
Mendelson, Jack, H., Mello, Nancy, K.
core   +1 more source

Adaptive Cu Reconstruction in Heterostructure Drives High‐Rate Nitrate‐to‐Ammonia Conversion

Advanced Science, EarlyView.
An adaptively reconstructed Cu/CoOX heterojunction, featuring a surface‐localized, hydroxyl‐rich oxidized Cu species, forms in situ from a CuO/CoOX (Co1Cu9OX) pre‐catalyst during electrochemical nitrate reduction. The self‐adaptive reconstruction and the incorporation of heterostructure regulate nitrogen‐containing intermediate adsorption and *H supply,
Chunyu Yuan, Saikat Bolar, Yongzheng Zhang, Akitaka Ito, Tatsuhiko Ohto, Takeshi Fujita   +5 more
wiley   +1 more source

A differential role for neuropeptides in acute and chronic adaptive responses to alcohol: behavioural and genetic analysis in Caenorhabditis elegans.

PLoS ONE, 2010
Prolonged alcohol consumption in humans followed by abstinence precipitates a withdrawal syndrome consisting of anxiety, agitation and in severe cases, seizures.
Philippa Mitchell, Richard Mould, James Dillon, Steven Glautier, Ioannis Andrianakis, Christopher James, Amanda Pugh, Lindy Holden-Dye, Vincent O'Connor   +8 more
doaj   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Phosphatidylethanol levels and their association with withdrawal severity among individuals with severe alcohol use disorder seeking inpatient withdrawal management

Frontiers in Psychiatry
IntroductionThis study aimed to determine if phosphatidylethanol (PEth) levels are associated with alcohol withdrawal severity among individuals seeking inpatient withdrawal management.MethodsA prospective study enrolled individuals undergoing alcohol ...
Jeong Hoo Lee, Jeong Hoo Lee, Veronica Szpak, Lisa W. Vercollone, Peter R. Chai, Peter R. Chai, Charlotte E. Goldfine, Charlotte E. Goldfine, Samuel Maddams, Joji Suzuki, Joji Suzuki   +10 more
doaj   +1 more source

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source