Results 31 to 40 of about 169,614 (312)

Liver transplantation for alcoholic liver disease [PDF]

open access: yesClinical Liver Disease, 2013
Alcoholism is a disease of remission and relapse. A lapse in abstinence tends to be viewed as a failure to commit to abstinence, and an acknowledged relapse may lead to the patient's removal from the liver transplant list; however, such a relapse may actually offer insight into alcoholism.
Patrizia, Burra, Michael R, Lucey
openaire   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Liver Transplants for Alcoholic Liver Disease

open access: yesCanadian Journal of Gastroenterology, 1991
Alcohol related end-stage liver disease is a principal cause of liver failure. The scarcity of donor livers and the predominance of alcohol related end-stage liver disease has raised the issue of including alcoholics as candidates for liver ...
RJ Fingerote, VG Bain, RN Fedorak
doaj   +1 more source

Lifestyle modification in NAFLD/NASH: Facts and figures

open access: yesJHEP Reports, 2019
Summary: The development of non-alcoholic fatty liver disease is closely linked to lifestyle factors, namely excessive caloric intake coupled with reduced physical activity and exercise. This review aims to examine the evidence behind lifestyle change as
Kate Hallsworth, Leon A. Adams
doaj   +1 more source

Microbiota, Liver Diseases, and Alcohol

open access: yesMicrobiology Spectrum, 2017
ABSTRACTBeing overweight and obesity are the leading causes of liver disease in Western countries. Liver damage induced by being overweight can range from steatosis, harmless in its simple form, to steatohepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. Alcohol consumption is an additional major cause of liver disease.
Gerard, Philippe   +2 more
openaire   +4 more sources

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

The Role of Nitric Oxide and Ferritin in the Pathogenesis of Alcoholic Liver Disease: a Controlled Clinical Study

open access: yesBiomolecules & Biomedicine, 2009
The role of ferritin in fibrogenesis of liver parenchyma in patients with alcoholic liver disease has been investigated in previous studies. Ferritin was shown to be an indirect marker of ferum deposition in liver parenchyma in alcohol liver disease. The
Azra Husić-Selimović   +4 more
doaj   +1 more source

Primary care and referring physician perspectives on non-alcoholic fatty liver disease management: a nationwide survey

open access: yesTherapeutic Advances in Gastroenterology, 2021
Introduction: The optimal approach to screening and risk stratification for non-alcoholic fatty liver disease is challenging given disease burden and variable progression. The aim of this study was to assess primary care physician and referring physician
Naba Saeed   +6 more
doaj   +1 more source

The presence of diabetic retinopathy closely associated with the progression of non-alcoholic fatty liver disease: A meta-analysis of observational studies

open access: yesFrontiers in Molecular Biosciences, 2022
Background and Objective: Although growing evidence indicates that non-alcoholic fatty liver disease is related to diabetic retinopathy (DR), research results significantly vary.
Guo-heng Zhang   +7 more
doaj   +1 more source

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