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, 1978 Newsletter of the Texas Commission on Alcoholism providing updates the agency and their programs along with news, events, and other information related to addiction prevention and ...
Orr, Bonnie +1 more
core +4 more sources
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
Hepatology, EarlyView., 2022 EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu +16 more
wiley +1 more source
Sleep disturbances are associated with cortical and subcortical atrophy in alcohol use disorder
Translational Psychiatry, 2021 Sleep disturbances are prominent in patients with alcohol use disorder (AUD) and predict relapse. So far, the mechanisms underlying sleep disruptions in AUD are poorly understood.
Rui Zhang +11 more
doaj +1 more source
Journal of Neuroinflammation, 2023 Background Neuroinflammation is a widely studied phenomenon underlying various neurodegenerative diseases. Earlier study demonstrated that pharmacological activation of GPR110 in both central and peripheral immune cells cooperatively ameliorates ...
Sharmistha Banerjee +3 more
doaj +1 more source
Cell Death Discovery, 2023 The proliferation and differentiation of hepatic progenitor cells (HPCs) drive the homeostatic renewal of the liver under diverse conditions. Liver regeneration is associated with an increase in Axin2+Cnr1+ HPCs, along with a marked increase in the ...
Bani Mukhopadhyay +8 more
doaj +1 more source
Increased transcription of TSPO, HDAC2, and HDAC6 in the amygdala of males with alcohol use disorder
Brain and Behavior, 2021 Introduction Repeated exposure to high doses of alcohol triggers neuroinflammatory processes that contribute to craving and mood dysfunction in alcohol use disorder (AUD).
Luana Martins De Carvalho +4 more
doaj +1 more source
Frontiers in Psychiatry, 2023 BackgroundFear of COVID-19 is a risk factor for anxiety and depressive symptoms. During the COVID-19 pandemic, drinking to cope with psychological distress has been proposed as a key mechanism leading to problematic drinking.
Jeremy W. Luk +8 more
doaj +1 more source
Frontiers in Psychiatry, 2019 Opioid use in the United States has steadily risen since the 1990s, along with staggering increases in addiction and overdose fatalities. With this surge in prescription and illicit opioid abuse, it is paramount to understand the genetic risk factors and
Jamie A. Burns +8 more
doaj +1 more source
ALCOHOL AND ALCOHOLIC INTOXICATION.* [PDF]
British Journal of Inebriety, 1920 n ...
openaire +2 more sources