Results 51 to 60 of about 118,083 (262)

Naloxone precipitated withdrawal increases dopamine release in the dorsal striatum of opioid dependent men

open access: yesTranslational Psychiatry, 2021
Dopamine (DA) neurotransmission is critical in the neurobiology of reward and aversion, but its contribution to the aversive state of opioid withdrawal remains unknown in humans.
Ehsan Shokri-Kojori   +2 more
doaj   +1 more source

Hours Since Last Drink Is Associated With Multiple Urine Ethyl Glucuronide Cutoffs Among Individuals With Alcohol Use Disorder

open access: yesDrug Testing and Analysis, EarlyView.
Higher uEtG results indicated more recent drinking, rather than higher levels of alcohol consumption, and the period of detection of uEtG was shorter than previously reported. Even at low cutoffs, uEtG was best conceptualized as a measure of alcohol consumption in the prior 24 h.
Julianne D. Jett   +10 more
wiley   +1 more source

Longitudinal gut microbiome changes in alcohol use disorder are influenced by abstinence and drinking quantity

open access: yesGut Microbes, 2020
Many patients with alcohol use disorder (AUD) consume alcohol chronically and in large amounts that alter intestinal microbiota, damage the gastrointestinal tract, and thereby injure other organs via malabsorption and intestinal inflammation.
Nancy J. Ames   +13 more
doaj   +1 more source

ALCOHOLISM. [PDF]

open access: yesThe Lancet, 1902
n ...
openaire   +2 more sources

Incident heart failure: comparing management and outcome in primary and hospital settings in Western Sweden 2008–2017

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 832-838, April 2025.
Abstract Aim Heart failure (HF) is a highly prevalent condition managed in both primary care (PC) and hospital care (HC)‐based settings. HF patients managed in these two settings may differ in their demography, comorbidities and outcomes, so we aimed to compare the patient management in PC and HC in the Västra Götaland Region (VGR) in Sweden.
Xiaojing Chen   +4 more
wiley   +1 more source

Brain asymmetry and its association with inattention and heritability during neurodevelopment

open access: yesTranslational Psychiatry
The relationship between brain asymmetry and inattention, and their heritability is not well understood. Utilizing advanced neuroimaging, we examined brain asymmetry with data from the Adolescent Brain Cognitive Development (ABCD; n = 8943; 9–10 y) and ...
Dardo Tomasi, Nora D. Volkow
doaj   +1 more source

Gestational alcohol exposure disrupts cognitive function and striatal circuits in adult offspring

open access: yesNature Communications, 2020
Alcohol is the leading cause of preventable birth defects in the US, collectively referred to as Fetal Alcohol Spectrum Disorder. Here, the authors show that fetal alcohol exposure induces lasting neurophysiological changes in dorsal striatum that ...
Verginia C. Cuzon Carlson   +2 more
doaj   +1 more source

A contemporary simple risk score for prediction of severe acute kidney injury after heart transplantation

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1166-1175, April 2025.
A contemporary simple risk score for prediction of severe AKI after HT. Abstract Background The aim of this study was to develop a simple risk score to estimate severe acute kidney injury (AKI) risk based on a large contemporary heart transplantation (HT) cohort.
Shuangshuang Zhu   +10 more
wiley   +1 more source

Frequency of anti‐neural antibodies and autoimmune epilepsy in focal epilepsy of unknown etiology: An observational study in a Singaporean cohort

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Autoimmune epilepsy (AES) is increasingly recognized as a condition in patients with epilepsy of unknown etiology. Early immunotherapy improves outcomes; however, data on its prevalence and the frequency of anti‐neural/neuronal antibodies in Asian populations remain scarce.
Seong Jin Park   +14 more
wiley   +1 more source

Understanding the Symptom Burden of Complex Skull Base Tumors From the Patient's Perspective

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Symptom burden of skull base tumor (SBT) patients, especially those undergoing multimodality treatment, is poorly understood. We aim to understand symptom burden in this patient group using the core module the MD Anderson Symptom Inventory (MDASI).
Shirley Y. Su   +8 more
wiley   +1 more source

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