Results 11 to 20 of about 34,905 (216)

TRAIP Mediates Alcohol-Induced Liver Injury through Regulating β-catenin Ubiquitin Degradation via Direct Interaction. [PDF]

Adv Sci (Weinh)
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Wu Z, Liu M, Liao L, Mo Z, Xu W, Mao L, Chen Y, Xie Q, Yao M, Chen S, Tomlinson S, Mueller S, He S, Yuan G.   +13 more
europepmc   +2 more sources

Temperature evolution and grain defect formation during single crystal solidification of a blade cluster [PDF]

China Foundry, 2017
In order to investigate the asymmetry of thermal conditions during directional solidification, the temperature evolution and correspondingly developed undercooling in a simplified single crystal blade cluster were numerically simulated.
De-xin Ma, Fu Wang, Qiang Wu
doaj   +1 more source

The Practice of Retransplantation for Recurrent Alcohol-associated Liver Disease in the United States Is Uncommon With Acceptable Outcomes

Transplantation Direct, 2022
Background. Alcohol-associated liver disease (ALD) is the leading indication for liver transplantation (LT) in the United States. Alcohol use disorder relapse can lead to graft failure and the need for liver retransplantation (re-LT).
Thomas G. Cotter, MD, MS, Matthew A. Odenwald, MD, PhD, Sarah R. Lieber, MD, MSCR, Nicole E. Rich, MD, Gene Im, MD, Michael Charlton, MD, Amit G. Singal, MD, Mack C. Mitchell, MD   +7 more
doaj   +1 more source

Targetable Brg1‐CXCL14 axis contributes to alcoholic liver injury by driving neutrophil trafficking

EMBO Molecular Medicine, 2023
Alcoholic liver disease (ALD) accounts for a large fraction of patients with cirrhosis and hepatocellular carcinoma. In the present study we investigated the involvement of Brahma‐related gene 1 (Brg1) in ALD pathogenesis and implication in ALD ...
Nan Li, Hong Liu, Yujia Xue, Zheng Xu, Xiulian Miao, Yan Guo, Zilong Li, Zhiwen Fan, Yong Xu   +8 more
doaj   +1 more source

Reducing the Process Energy through Applying Plasma in Atomic Layer Deposition of Solid Oxide Fuel Cell Electrolyte [PDF]

한국정밀공학회지, 2019
The energy saving effect of reactant plasma in Atomic Layer Deposition (ALD) of ultrathin solid oxide fuel cell electrolyte was examined by measuring electrical current in real time.
Sanghoon Ji
doaj   +1 more source

Coexisting Volatile and Nonvolatile Switching in 3D ALD-IGZO Vertical RRAM for Fully Hardware-Based Wide Reservoir Computing. [PDF]

Adv Sci (Weinh)
A conformal ALD‐IGZO vertical RRAM integrates volatile and nonvolatile switching within a compact 2F architecture. Before forming, tunable volatile dynamics provide fading‐memory reservoir states, while after forming, stable multilevel conductance modulation enables hardware readout.
Lee S, Park J, Kim N, Ju S, Jang SC, Kim HS, Kim S.   +6 more
europepmc   +2 more sources

Düzeltme: Dynamics in between Structural and Electrical Properties of as Grown ZnO Thin Films by Thermal ALD

Gazi Üniversitesi Fen Bilimleri Dergisi
The mechanism behind n-type conductivity of undoped ZnO films are not understood well. One and two dimensional defects (grain boundaries, dislocations), and zero dimensional stoichiometric point defects (vacancies, self-interstitials and impurities) play
Bilge İmer
doaj   +1 more source

Increased age, bilirubin, international normalized ratio, and creatinine score to triglyceride ratio are associated with alcohol-associated primary liver carcinoma: a single-centered retrospective study

Lipids in Health and Disease, 2023
Background This study analyzed the clinical features and biomarkers of alcohol-associated liver disease (ALD) to investigate the diagnostic value of age, bilirubin, international normalized ratio (INR), and creatinine (ABIC) score to triglyceride (TG ...
Xiaoqing Jia, Rong Li, Xiaoting Zhang, Tao Zhou, Dalong Sun, Na Yang, Zheng Luo   +6 more
doaj   +1 more source

Mitochondrial ROS, a trigger for mitochondrial dysfunction and inflammasome activation and a therapeutic target in liver diseases

Exploration of Digestive Diseases
Mitochondria are essential organelles responsible for intracellular energy production and play crucial roles in cellular metabolism, inflammation, and apoptosis.
Hala Saeed Jaara, Sandra Torres
doaj   +1 more source

Global epidemiology of alcohol-related liver disease, liver cancer, and alcohol use disorder, 2000–2021 [PDF]

Clinical and Molecular Hepatology
Background/Aims Alcohol represents a leading burden of disease worldwide, including alcohol use disorder (AUD) and alcohol-related liver disease (ALD). We aim to assess the global burden of AUD, ALD, and alcohol-attributable primary liver cancer between ...
Pojsakorn Danpanichkul, Luis Antonio Díaz, Kanokphong Suparan, Primrose Tothanarungroj, Supapitch Sirimangklanurak, Thanida Auttapracha, Hanna L. Blaney, Banthoon Sukphutanan, Yanfang Pang, Siwanart Kongarin, Francisco Idalsoaga, Eduardo Fuentes-López, Lorenzo Leggio, Mazen Noureddin, Trenton M. White, Alexandre Louvet, Philippe Mathurin, Rohit Loomba, Patrick S. Kamath, Jürgen Rehm, Jeffrey V. Lazarus, Karn Wijarnpreecha, Juan Pablo Arab   +22 more
doaj   +1 more source