Results 191 to 200 of about 112,433 (285)

Diagnostic Impacts of Aldehyde Dehydrogenase 2 Genetic Variants on Hepatocellular Carcinoma Susceptibility. [PDF]

open access: yesCancer Diagn Progn
Chin YT   +10 more
europepmc   +1 more source

Asymmetric Synthesis of Atropisomeric Amines via Transaminase‐Catalyzed Dynamic Kinetic Resolution

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 2, January 2026.
A dynamic kinetic resolution approach is developed for the atroposelective synthesis of heterobiaryl primary amines. Using transaminases and leveraging Lewis acid‐base interactions to induce racemization, a variety of axially chiral primary amines are produced in high yields and enantioselectivities.
Juan M. Coto‐Cid   +8 more
wiley   +1 more source

Exploring the Role and Pathophysiological Significance of Aldehyde Dehydrogenase 1B1 (ALDH1B1) in Human Lung Adenocarcinoma. [PDF]

open access: yesInt J Mol Sci
Tsochantaridis I   +11 more
europepmc   +1 more source

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang   +6 more
wiley   +1 more source

Human aldehyde dehydrogenase

open access: yesJournal of Biological Chemistry, 1989
G Kurys, W Ambroziak, R Pietruszko
openaire   +1 more source

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen   +11 more
wiley   +1 more source

Genome‐scale Metabolic Modeling Guided Escherichia coli Engineering for De Novo Biosynthesis of Chrysanthemic Acid

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
Genome‐scale metabolic modeling is preceded to the engineered E. coli cell factory for the de novo biosynthesis of biopesticide chrysanthemic acid. The debranching strategy redirects metabolic flux, enhancing precursor and target compound production.
Jiangpeng Yu   +6 more
wiley   +1 more source

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