Results 211 to 220 of about 112,433 (285)

Brain Aldehyde Dehydrogenase

Journal of Biological Chemistry, 1966
V. Gene Erwin, Richard A. Deitrich
openaire   +1 more source

The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha, Danielle Twilley, Mona Dawood, Thomas Efferth, Namrita Lall   +4 more
wiley   +1 more source

Reactive oxygen species and aldehyde dehydrogenase 1A as prognosis and theragnostic biomarker in acute myeloid leukaemia patients. [PDF]

J Cell Mol Med
Venton G, Colle J, Tichadou A, Quessada J, Baier C, Labiad Y, Perez M, De Lassus L, Loosveld M, Arnoux I, Abbou N, Ceylan I, Martin G, Costello R.   +13 more
europepmc   +1 more source

Ethylene Glycol Poisoning With Oxalate Nephropathy and Acute Kidney Injury: A Case Report and Review of the Literature

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Ethylene glycol (EG) is a hazardous alcohol present in various household and industrial products. After being metabolized by ethanol dehydrogenase and aldehyde dehydrogenase, it can produce glycolate, acetaldehyde, and oxalate, leading to acute kidney injury.
Zhenjian Xu, Yanling Dai, Yanling You, Yanjun Huang, Hong Chen, Hongbo Ye, Shuling Yue, Qiongqiong Yang   +7 more
wiley   +1 more source

Reduced aldehyde dehydrogenase 2 in respiratory tract associates with dysregulated alcohol metabolism and respiratory reactions in aspirin-exacerbated respiratory disease. [PDF]

J Allergy Clin Immunol
Zawacki M, Huang GX, Cho L, Omilabu V, Bensko JC, Roditi RE, Lee SE, Barrett NA, Buchheit KM, Laidlaw TM.   +9 more
europepmc   +1 more source

Bioreduction of β‐ketosulfides Using Deep Eutectic Solvents as Cosolvents

ChemCatChem, Volume 18, Issue 2, 28 January 2026.
A set of β‐ketosulfides has been selectively reduced to optically active β‐hydroxysulfides employing KREDs as biocatalysts in the presence of Deep Eutectic Solvents. By appropriately selecting both the biocatalyst and the reaction medium, both alcohol enantiomers can be obtained in high yields and optical purities.
Chiara Falcini, Juan Carvajal‐Bárcena, Lucía V. Urban, Juan Pablo Colomer, Fabricio R. Bisogno, Rosario Fernández, Gonzalo de Gonzalo   +6 more
wiley   +1 more source

Enzymatic Control of Alcohol Metabolism in the Body-The Roles of Class I, II, III, and IV Alcohol Dehydrogenases/NADH Reoxidation System, Microsomal Ethanol Oxidizing System, Catalase/H₂O₂ System, and Aldehyde Dehydrogenase 2. [PDF]

Int J Mol Sci
Haseba T.
europepmc   +1 more source

Biological Conversion of Formate to Organic Compounds: Toward a Sustainable Formate Bioeconomy

Carbon Energy, Volume 8, Issue 1, January 2026.
Formate bioconversion plays a crucial role in achieving renewable resource utilization and sustainable development. To tap its full potential, it is important to identify the most appropriate microbial hosts for incorporating formate into building blocks, design the most promising metabolic pathways for transmitting formate into central carbon ...
Jinyi Qian, Tiantian Chai, Chunlei Zhao, Xiulai Chen   +3 more
wiley   +1 more source

Self-assembled aldehyde dehydrogenase-activatable nano-prodrug for cancer stem cell-enriched tumor detection and treatment. [PDF]

Nat Commun
Li B, Tian J, Zhang F, Wu C, Li Z, Wang D, Zhuang J, Chen S, Song W, Tang Y, Ping Y, Liu B.   +11 more
europepmc   +1 more source

AARS1‐mediated AKR1B10 lactylation stabilizes an aerobic glycolysis‐positive feedback loop to drive lenvatinib resistance in hepatocellular carcinoma

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
AKR1B10 confers lenvatinib resistance by enhancing aerobic glycolysis in HCC cells. AKR1B10 undergoes AARS1‐mediated lactylation at K173, stabilizing it by antagonizing ubiquitin‐proteasomal degradation. AKR1B10 promotes LDHA Y10 phosphorylation, boosting lactate production, which drives H3K18la‐mediated transcriptional upregulation of LDHA, creating a
Zijian Liu, Jingsheng Yuan, Shitong Su, Jiaqi Han, Ni Zeng, Yuhan Ma, Nianyong Chen, Tao Lv   +7 more
wiley   +1 more source