Results 61 to 70 of about 436,306 (274)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Microarray analysis of spring barley cultivars displaying differing sensitivity to physiological leaf spot (PLS) [PDF]

, 2015
peer-reviewedPhysiological leaf spot (PLS) is a disorder of spring barley (Hordeum vulgare L.), which has become more pronounced in recent years. The initial symptoms are small chlorotic/brown spots on the upper four leaves, which may develop into ...
Burke, James I., Dix, Philip J., Moran, Mary G.   +2 more
core   +1 more source

Aldose Reductase-catalyzed Reduction of Aldehyde Phospholipids [PDF]

Journal of Biological Chemistry, 2004
Oxidation of unsaturated phospholipids results in the generation of aldehyde side chains that remain esterified to the phospholipid backbone. Such "core" aldehydes elicit immune responses and promote inflammation. However, the biochemical mechanisms by which phospholipid aldehydes are metabolized or detoxified are not well understood.
Sanjay, Srivastava, Matthew, Spite, John O, Trent, Matthew B, West, Yonis, Ahmed, Aruni, Bhatnagar   +5 more
openaire   +2 more sources

In vivo Quantification of Alkanes in Escherichia coli

Bio-Protocol, 2020
Microbial production of alkanes employing synthetic biology tools has gained tremendous attention owing to the high energy density and similarity of alkanes to existing petroleum fuels. One of the most commonly studied pathways includes the production of
Tabinda Shakeel, Zia Fatma, Syed Shams Yazdani   +2 more
doaj   +1 more source

Construction and yield optimization of a cinnamylamine biosynthesis route in Escherichia coli

Biotechnology for Biofuels and Bioproducts, 2022
Background With the development of metabolic engineering and synthetic biology, the biosynthesis of aromatic compounds has attracted much attention. Cinnamylamine is an aromatic compound derived from l-phenylalanine, which is used in the synthesis of ...
Qi Wang, Linlin Ma, Zhiguo Wang, Quan Chen, Qian Wang, Qingsheng Qi   +5 more
doaj   +1 more source

Transcriptome pathways unique to dehydration tolerant relatives of modern wheat [PDF]

, 2009
Among abiotic stressors, drought is a major factor responsible for dramatic yield loss in agriculture. In order to reveal differences in global expression profiles of drought tolerant and sensitive wild emmer wheat genotypes, a previously deployed shock ...
AN Olsen, B Barnabas, B Vinocur, C Guy, D Bartels, DB Lobell, E Ormeno, EA Bray, G Toledo-Ortiz, GP Xue, GR Cramer, Hans J. Bohnert, HG Jones, Hikmet Budak, HJ Bohnert, IK Vasil, J Dubcovsky, J Zhou, JL Araus, Jyothi Thimmapuram, K Deuschle, K Higuchi, K Higuchi, K Poustini, K Shinozaki, L Cseke, L Rodriguez-Uribe, L Xiong, M Mohammadi, M Seki, MB Eisen, N Kaur, NC Collins, Neslihan Z. Ergen, O Cebeci, P Langridge, P Rampino, PBK Kishor, PY Muller, R Kaldenhoff, R Munns, S Chao, S Mahajan, S Ramanjulu, T Eulgem, The Gene Ontology Consortium, V Talame, W Li, W Wang, YG Shen, YH Lee, ZN Ergen, ZN Ergen, ZN Ozturk   +53 more
core   +1 more source

Comparative transcriptomic analysis unveils interactions between the regulatory CarS protein and light response in Fusarium [PDF]

, 2019
Background The orange pigmentation of the agar cultures of many Fusarium species is due to the production of carotenoids, terpenoid pigments whose synthesis is stimulated by light.
Limón Mirón, María del Carmen, Pardo Medina, Javier, Parra Rivero, Obdulia, Romero Campero, Francisco José, Ruger Herreros, María Macarena, Ávalos Cordero, Francisco Javier   +5 more
core   +1 more source

Metabolic Engineering of Saccharomyces cerevisiae for Enhanced Dihydroartemisinic Acid Production

Frontiers in Bioengineering and Biotechnology, 2020
Direct bioproduction of DHAA (dihydroartemisinic acid) rather than AA (artemisinic acid), as suggested by previous work would decrease the cost of semi-biosynthesis artemisinin by eliminating the step of initial hydrogenation of AA.
Bo-Xuan Zeng, Bo-Xuan Zeng, Ming-Dong Yao, Ming-Dong Yao, Ying Wang, Ying Wang, Wen-Hai Xiao, Wen-Hai Xiao, Ying-Jin Yuan, Ying-Jin Yuan   +9 more
doaj   +1 more source

Preussia sp. BSL-10 producing nitric oxide, gibberellins, and indole acetic acid and improving rice plant growth

Journal of Plant Interactions, 2018
Preussia sp. have been least known to improve plant growth and produce phytohormones. The current study investigated the production of nitric oxide (NO), indole-3-acetic acid (IAA), and gibberellins (GA4, GA7, GA15, and GA53) by a novel endophytic-fungal
Khdija Al-Hosni, Raheem Shahzad, Abdul Latif Khan, Qari Muhammad Imran, Ahmed Al Harrasi, Ahmed Al Rawahi, Sajjad Asaf, Sang-Mo Kang, Byung-Wook Yun, In-Jung Lee   +9 more
doaj   +1 more source

Development and exploration of novel substituted thiosemicarbazones as inhibitors of aldose reductase via in vitro analysis and computational study

Scientific Reports, 2022
The role of aldose reductase (ALR2) in causing diabetic complications is well-studied, with overactivity of ALR2 in the hyperglycemic state leading to an accumulation of intracellular sorbitol, depletion of cytoplasmic NADPH and oxidative stress and ...
Aqeel Imran, Muhammad Tariq Shehzad, Syed Jawad Ali Shah, Taha al Adhami, Mark Laws, Khondaker Miraz Rahman, Rima D. Alharthy, Imtiaz Ali Khan, Zahid Shafiq, Jamshed Iqbal   +9 more
doaj   +1 more source