Results 181 to 190 of about 194,755 (364)

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Aldehyde Oxidase: Reaction Mechanism and Prediction of Site of Metabolism

, 2017
Marco Montefiori, Flemming Steen Jørgensen, Lars Olsen   +2 more
openalex   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

Application of the semi-empirical topological index in quantitative structure-chromatographic retention relationship (QSRR) studies of aliphatic ketones and aldehydes on stationary phases of different polarity

Journal of the Brazilian Chemical Society, 2004
The semi-empirical topological index, previously developed by Heinzen and Yunes, has been applied to predict the chromatographic retention of aliphatic ketones and aldehydes on stationary phases of different polarities (HP-1, HP-50, DB-210 and Innowax ...
Junkes Berenice da S., Amboni Renata D. de M. C., Yunes Rosendo A., Heinzen Vilma E. F.   +3 more
doaj  

Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity

, 1999
Robert W. Storms, Aliana P. Trujillo, James B. Springer, Lisa Shah, O. Michael Colvin, Susan M. Ludeman, Clayton A. Smith   +6 more
openalex   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Advancements in the synthesis of naphthoxazine-3-one derivatives over the last two decades: a brief review. [PDF]

RSC Adv
Bankar DB, Shinde ST, Kanade KG, Amalnerkar DP, Takle SP.   +4 more
europepmc   +1 more source

Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance

Advanced Science, EarlyView.
Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes, Xiaokang Jin, Miguel A. Campos, Chen Zhou, Xiaoyu Zhang   +4 more
wiley   +1 more source

Immobilized Pd-EDTA complex supported on MnFe₂O₄ magnetic nanoparticles: a highly efficient and reusable new catalyst for esterification of aryl aldehydes. [PDF]

Discov Nano
Abushuhel M, Zaki MEA, Rekha MM, Basheer NM, Ray S, Pal A, Sharma R, Gomha SM, Singh A.   +8 more
europepmc   +1 more source