Direct Synthesis of Protected Secondary <i>N</i>‑Alkylamines via Reductive Amination of Aldehydes with Protected <i>N</i>‑Alkylamines Using Me<sub>2</sub>SiHCl. [PDF]
Ryu HW, Jeong M, Jeon H, Cheon CH.
europepmc +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Metal‐catalyzed enantioconvergent substitutions of unactivated cyclic electrophiles by organometallic nucleophiles have not previously been reported. Herein, a chiral nickel catalyst is described that achieves this objective, coupling 3‐iodopyrrolidine derivatives with arylzinc nucleophiles.
Ting Hei Matthew Wong +2 more
wiley +2 more sources
Characterization of key volatile compounds in meat-based broths using HS-SPME-Arrow-GC/MS and their relationship to sensory perception. [PDF]
Nam JK, Kim MR, Hyeon JE, Jang HW.
europepmc +1 more source
Diazo Transfer From Nitrous Oxide Employing Phosphorus Ylides
A phosphorus ylide‐mediated strategy achieves the direct fixation of nitrous oxide (N2O) to access diazo compounds, which after intra‐ or intermolecular trapping, afford N2‐containing organic building blocks. This approach provides an alternative to hazardous diazo‐transfer reagents and establishes N2O fixation as a sustainable methodology.
Jhen‐Kuei Yu +4 more
wiley +2 more sources
Direct Acylation of Alkyl and Aryl Bromides via Nickel-Catalyzed Aldehyde C-H Functionalization. [PDF]
Calvert SJ +6 more
europepmc +1 more source
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj +1 more source
Mechanism of flavor deterioration in chicken meat with varying degrees of wooden breast: Insights from integrated HS-GC-IMS and UPLC-MS/MS-based metabolomics. [PDF]
Lu H +7 more
europepmc +1 more source
Synthesis of vinyl boronates from aldehydes by a practical boron-Wittig reaction.
J. Coombs, Liang Zhang, J. Morken
semanticscholar +1 more source

