Results 101 to 110 of about 23,764 (226)
Targeting aberrant expression of Notch-1 in ALDH+ cancer stem cells in breast cancer
Molecular Carcinogenesis, 2016 We have previously reported that high aldehyde dehydrogenase (ALDH) enzyme activity in breast cancer cells results in breast cancer stem cell (BCSC) properties by upregualting Notch‐1 and epithelial mesenchymal markers. This results in chemoresistance in
Deeksha Pal +10 more
semanticscholar +1 more source
Organ Medicine, Volume 3, Issue 3, Page 171-185, September 2026.Patients with alcohol‐associated liver cirrhosis or acetaminophen (APAP) toxicity frequently develop anemia with iron metabolism disturbances. Dysregulation of hepcidin–ferroportin signaling, along with inflammation, oxidative stress, hypoxia, impaired intestinal iron absorption, malnutrition, and gastrointestinal bleeding, contributes to anemia ...
Debabrata Dash, Raj Kumar Koiri
wiley +1 more source
Hepatology Research, Volume 56, Issue 9, Page 1419-1425, September 2026.ABSTRACT Aim Genetic polymorphisms of alcohol‐metabolizing enzymes influence drinking behavior and susceptibility to alcohol‐related liver disease (ALD). This study aimed to clarify the distribution of ALDH2 and ADH1B genotypes in liver transplant recipients with ALD, and to explore associations with post‐transplant drinking behavior using a recipient ...
Noriyo Yamashiki +3 more
wiley +1 more source
BMC Cancer, 2012 Background The primary objective of this study was to test whether oncolytic herpes simplex virus type 1 (HSV1) could eradicate chemoresistant cancer stem cells (CSCs).
Zhuang Xiufen +8 more
doaj +1 more source
Mucosal Immunology, 2015 Disruption of the homeostatic balance of intestinal dendritic cells (DCs) and macrophages (MQs) may contribute to inflammatory bowel disease. We characterized DC and MQ populations, including their ability to produce retinoic acid, in clinical material ...
M. Magnusson +11 more
semanticscholar +1 more source
ALDEHID DEHIDROGENASE DALAM TIKUS WISTAR SEBAGAI BIOMARKER AWAL KONSUMSI ALKOHOL SECARA AKUT
Jurnal Biologi Udayana, 2011 Research on oral consumption of alcohol on rat Wistar was done to examine level of aldehyde dehydrogenase (ALDH) in rat serum. The research design was true randomized experimental post test only control group design.
NI MADE SUANITI +3 more
doaj
Molecules, 2019 Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer death among females globally. The tumorigenic activities of cancer cells such as aldehyde dehydrogenase (ALDH) activity and differentiation have contributed to relapse ...
Siyamak Ebrahimi Nigjeh +4 more
doaj +1 more source
OncoTarget, 2015 A small sub-population of cells characterized by increased tumorigenic potential, ability to self-renew and to differentiate into cells that make up the tumor bulk, has been characterized in some (but not all) tumor types. These unique cells, namedcancer
A. Adams +11 more
semanticscholar +1 more source
HEMATOPOETIK KÖK HÜCRE İZOLASYONUNDA ALDH ETKİNLİĞİNİN ÖNEMİ
Journal of Istanbul Faculty of Medicine / İstanbul Tıp Fakültesi Dergisi, 2017 Amac: Kan hucrelerine kolaylikla farklilasabilen hematopoetik kok hucrelerin (HKH) saflastirmasinda tercih edilen yontem, flow sitometrik veya magnetik ayirim sistemi ile CD34 + hucrelerin secimidir. Insan kok hucrelerini tamamen fenotipik hucre yuzey belirteclerine dayanmadan etkin olarak saptayan metodlara ihtiyac vardir.
TÜRKER ŞENER, Leyla +4 more
openaire +4 more sources
Ontogenesis and Expression of ALDH Activity in the Skin and the Eye of the Rat
, 1996 As the body’s first line of defense against external insult, both the eye and the skin are exposed routinely to chemical agents, serving as a portal of entry for topical contactants. In addition, global atmospheric changes like ozone depletion in the stratosphere contribute to enhanced chronic exposure of the skin and the eye of human tissue to UV ...
Pappas, P. +4 more
openaire +3 more sources