Results 91 to 100 of about 23,764 (226)
Cancer Medicine, Volume 15, Issue 9, September 2026.Cancer stem cell quiescence is a regulated, reversible survival mechanism, preserving stemness and promoting therapy resistance through intrinsic programs and niche signals. Targeting these pathways holds promise for eradicating quiescent CSCs and preventing recurrence.
Yasin Ahmadi +3 more
wiley +1 more source
Chronic Paraquat Neurotoxicity and Dopaminergic Degeneration: A Mechanistic Review
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.Occurrence of Parkinson's disease (PD) based on several neurotoxins. Advanced and comprehensive mechanisms based on Paraquat‐induced PD. Mechanism of oxidative stress, ROS and RNS formation, and death of dopaminergic neurons. The modulation of genes and proteins by paraquat leads to Parkinsonism.
Saima Riaz +5 more
wiley +1 more source
Efficacy of an ALDH peptide-based dendritic cell vaccine targeting cancer stem cells
Cancer Immunology and Immunotherapy, 2022 F. Liao +9 more
semanticscholar +1 more source
Archives of medical science : AMS, 2017 Introduction Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) exist in the brain. Alcohol dehydrogenase and ALDH are also present in brain tumor cells.
W. Jelski +5 more
semanticscholar +1 more source
Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 5, September 2026.ABSTRACT Objective This review critically examines psilocybin, with particular emphasis on its pharmacokinetics and pharmacodynamics, including its serotonergic, neuroplastic, and anti‐inflammatory mechanisms. It integrates historical context, preclinical and clinical evidence, and evaluates emerging therapeutic potential, safety, microdosing practices,
José Norberto Vásquez‐Bonilla
wiley +1 more source
EGFL6 regulates the asymmetric division, maintenance and metastasis of ALDH+ ovarian cancer cells
Cancer Research, 2016 Little is known about the factors that regulate the asymmetric division of cancer stem-like cells. Here we demonstrate that EGFL6, a stem cell regulatory factor expressed in ovarian tumor cells and vasculature, regulates ALDH+ ovarian cancer stem-like ...
Shoumei Bai +12 more
semanticscholar +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.Alcohol metabolism induces structural instability of iron‐sulfur clusters through ROS‐mediated oxidative damage and direct covalent modification of acetaldehyde. The iron‐sulfur cluster deficiency drives metabolic reprogramming by inactivating aconitase, accumulating succinate, and impairing tRNA thiolation, thereby promoting hepatic steatosis ...
Li Xu +6 more
wiley +1 more source
PLoS ONE, 2013 Persistence of leukemic stem cells (LSC) after chemotherapy is thought to be responsible for relapse and prevents the curative treatment of acute myeloid leukemia (AML) patients.
Gerrit J Schuurhuis +10 more
doaj +1 more source
International Journal of Oncology, 2016 Persistent activation of signal transducers and activators of transcription 3 (STAT3) is commonly detected in many types of cancer including pancreatic cancer.
Li Lin +9 more
semanticscholar +1 more source
Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.ABSTRACT Phosphomannomutase deficiency (PMM2‐CDG), the most common congenital disorder of glycosylation (CDG), is characterized by multisystem involvement and a lack of disease‐modifying therapies. While previous transcriptomic studies have uncovered disrupted cellular pathways, the functional consequences of these alterations remain poorly understood.
Diana Gallego +10 more
wiley +1 more source