Results 91 to 100 of about 36,291 (209)

Assessment of Allergenic Potential for Cross‐Reactivity of Olive (Olea europaea) Pit Xylo‐Oligosaccharide‐Rich Extract With Legislated Allergens in the European Union

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
Spray‐dried xylo‐oligosaccharide‐rich extract derived from olive pit endocarps was assessed for potential cross‐reactivity using in vitro ELISA and in silico approaches. The ELISA tests indicated potential cross‐reactivities with nuts (hazelnut, almond, pistachio, peanut), gluten, and milk in certain batches.
Maame Ekua Manful   +4 more
wiley   +1 more source

Beyond a Metabolite: Lactylation as a Pivotal Regulator of Colorectal Cancer Pathogenesis and Treatment Resistance

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
This review elucidates how lactylation, a novel histone modification driven by lactate, regulates colorectal cancer pathogenesis. We summarize its roles in tumor progression, metastasis, stemness, immunosuppression, and therapy resistance, and discusses the promising therapeutic strategies of targeting the lactylation pathway.
Shuilan Yao   +4 more
wiley   +1 more source

DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity

open access: yesSmall, Volume 22, Issue 43, 3 August 2026.
DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley   +1 more source

An unattended image‐processing pipeline for on‐the‐fly quality assessment and 3D exploration in cryo‐EM

open access: yesActa Crystallographica Section D, Volume 82, Issue 8, Page 915-939, August 2026.
We present a fully automated, unattended cryo‐EM pipeline that serves as an on‐the‐fly diagnostic tool, enabling rapid data‐quality assessment and informed decision‐making to maximize data‐collection efficiency.Single‐particle analysis (SPA) by cryogenic electron microscopy (cryo‐EM) has become a cornerstone of structural biology; yet, the workflow ...
Daniel Marchán Torres   +14 more
wiley   +1 more source

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

open access: yesAllergy, Volume 81, Issue 8, Page 2744-2774, August 2026.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas   +128 more
wiley   +1 more source

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

open access: yesCell Proliferation, Volume 59, Issue 8, August 2026.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik   +10 more
wiley   +1 more source

Intra‐annual transfer of hydrogen and oxygen isotopic signals from water and sugar precursors to tree rings: Processes and mechanisms

open access: yesNew Phytologist, Volume 251, Issue 3, Page 1143-1160, August 2026.
Intra‐annual radial growth of beech and spruce in 2021 and 2022. Summary The oxygen (δ18O) and hydrogen (δ2H) isotope compositions of leaf and xylem water shape tree‐ring isotope baselines, while the fraction of sugars undergoing isotopic modification downstream of leaves (fO, fH) determines the dominant hydrologic signal.
Haoyu Diao   +10 more
wiley   +1 more source

CRYSTALLINE ALDOLASE

open access: yesJournal of Biological Chemistry, 1948
J F, TAYLOR, A A, GREEN, G T, CORI
openaire   +2 more sources

Polyphenol oxidase depletion in Nicotiana benthamiana enhances recombinant protein purification and preserves native protein integrity

open access: yesNew Phytologist, Volume 251, Issue 3, Page 1283-1293, August 2026.
Polyphenol oxidases (PPOs) depletion preserves endogenous proteins at their predicted molecular weights and enhances detectable enzymatic activities. (a) Less RbcL crosslinking in ppo mutant of Nicotiana benthamiana. Leaf extracts were incubated for 1 h, separated on protein gels, stained with Coomassie or analyzed by Western blot with the anti‐RbcL ...
Kaijie Zheng   +4 more
wiley   +1 more source

Kinetic parameter prediction using neural networks identifies limitations to C4 photosynthesis

open access: yesNew Phytologist, Volume 251, Issue 3, Page 1578-1594, August 2026.
Schematic overview of the generation of artificial training data and training of neural networks in C4TUNE. Summary Kinetic models of photosynthesis enable time‐resolved predictions of traits related to this key process and provide the means to identify factors limiting photosynthesis.
Philipp Wendering   +4 more
wiley   +1 more source

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