Results 91 to 100 of about 21,208,579 (315)

The glycolytic enzyme phosphofructokinase-1 assembles into filaments. [PDF]

, 2017
Despite abundant knowledge of the regulation and biochemistry of glycolytic enzymes, we have limited understanding on how they are spatially organized in the cell.
Albe, Anne M. Dosey, Attanasio, Barry, Beaty, Beckner, Bradley A. Webb, Brüser, Clarke, Cohen, De Bock, Diane L. Barber, Egelman, Egelman, Eisenberg, Foe, Frey, Gunning, Habrian, Ingerson-Mahar, Jang, Jia, Justin M. Kollman, Kemp, Kim, Lander, Li, Liu, Mahboubi, Meredith, Noree, Olsen, O’Connell, Ranjit, Reinhart, Rohou, Scheres, Scheres, Schindelin, Segall, Shaikh, Shen, Sievers, Stehbens, Stehbens, Suloway, Torsten Wittmann, Trujillo, Wang, Webb   +49 more
core   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Enzimas séricas e eletromiografia em doenças Neuromusculares: estudo comparativo de 817 casos

Arquivos de Neuro-Psiquiatria, 1995
Foram estudadas as enzimas séricas (creatinaquinase, desidrogenase láctica, aldolase, aspartato e alanina aminotransferase) de 817 pacientes e eletromiografias (EMG) de 588 casos de portadores de doenças neuromusculares.
Lineu Cesar Werneck
doaj   +1 more source

Quo vadis photorespiration: A tale of two aldolases

FEBS Letters, 1996
An O2‐consuming side reaction of d‐ribulose 1,5‐bisphosphate carboxylase causes photorespiration in plants. This reaction may be an inevitable consequence of the enzyme's inability to protect its ene‐diolate reaction intermediate from O2, a notion that is supported by the failure of persistent efforts to eliminate selectively its oxygenase activity by ...
Hixon, Mark, Sinerius, Gudrun, Schneider, Achim, Walter, Christiane, Fessner, Wolf-Dieter, Schloss, John V.   +5 more
openaire   +2 more sources

OSA Initiates Histone Lactylation That Drives PDE4B/FUS/AGT Axis to Pulmonary Hypertension

Cell Proliferation, EarlyView.
This study illustrates how chronic intermittent hypoxia (CIH) in obstructive sleep apnea (OSA) leads to hypertension via increased oxidative stress and mitochondrial dysfunction in pulmonary artery smooth muscle cells (PASMCs), causing glycolytic dysregulation. Lactate accumulation enhances histone lactylation, upregulating phosphodiesterase 4B (PDE4B),
Li Yang, Qing Ni, Yan He, Shijie Liu, Lulu Gan, Anni Dai, Yang Hu, Qian Liu, Xueling Yang, Jiqian Li, Yi Tao, Yunyu Li, Mingyue Xu   +12 more
wiley   +1 more source

Efeito do exercício físico intenso nas concentrações sérica, salivar e urinária de marcadores de lesão músculo esquelética

Evidência, 2018
A lesão muscular esquelética é um evento frequente entre os atletas. O diagnóstico utilizando os marcadores sanguíneos clássicos às vezes produz resultados insatisfatórios em razão da grande variabilidade interindividual.
Eduardo Ottobelli Chielle, Jorlana Stake Maziero   +1 more
doaj   +1 more source

Aldolase A Accelerates Cancer Progression by Modulating mRNA Translation and Protein Biosynthesis via Noncanonical Mechanisms

Advanced Science, 2023
Aldolase A (ALDOA), a crucial glycolytic enzyme, is often aberrantly expressed in various types of cancer. Although ALDOA has been reported to play additional roles beyond its conventional enzymatic role, its nonmetabolic function and underlying ...
Junjiao Song, Hongquan Li, Yanfang Liu, Xinrong Li, Qili Shi, Qun‐Ying Lei, Weiguo Hu, Shenglin Huang, Zhiao Chen, Xianghuo He   +9 more
doaj   +1 more source

Sensor potency of the moonlighting enzyme-decorated cytoskeleton [PDF]

, 2013
Background: There is extensive evidence for the interaction of metabolic enzymes with the eukaryotic cytoskeleton. The significance of these interactions is far from clear.
Amar Patrick, Legent Guillaume, Norris Vic, Ovádi Judit, Ripoll Camille, Thellier Michel   +5 more
core   +4 more sources

Update on diagnosis, nonpharmacological treatment and prevention of Equine Gastric Ulcer Syndrome (EGUS)

Equine Veterinary Education, EarlyView.
Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley   +1 more source

Two essential light chains regulate the MyoA lever arm to promote Toxoplasma gliding motility [PDF]

, 2015
Key to the virulence of apicomplexan parasites is their ability to move through tissue and to invade and egress from host cells. Apicomplexan motility requires the activity of the glideosome, a multicomponent molecular motor composed of a type XIV myosin,
Alonso, Hernan, Egarter, Saskia, Enciso, Marta, Meissner, Markus, Sheiner, Lilach, Smith, Brian J., Striepen, Boris, Tonkin, Christopher J., Williams, Melanie J.   +8 more
core   +2 more sources