Results 131 to 140 of about 21,208,579 (315)

Mass Spectrometry Imaging Combined With Single‐Cell Transcriptional Profiling Reveals the Multidimensional Spatial Distributions and Biosynthetic Pathways of Medicinal Components in Andrographis paniculata

Plant Biotechnology Journal, EarlyView.
ABSTRACT The synthesis and accumulation of active ingredients in medicinal plants are distributed in specific organs, tissues, and cell types, which are important for the exploitation of medicinal plants. However, the fine distribution of active ingredients is difficult to know. Here, the system of mass spectrometry imaging (MSI) integrated with single‐
HaiSheng Zeng, MeiHui Shi, ZhiRong Chen, XueJing Sun, HuiJie Zhang, Yue Huang, YuCheng Chen, Jun Ren, HuiLing Huang, Almaz Borjigidai, Man Zhang, SuJuan Duan, Yi‐Jun Chen, Hong‐Lei Jin, Hong‐Bin Wang   +14 more
wiley   +1 more source

Absolute diffusion measurements of active enzyme solutions by NMR

, 2018
The diffusion of enzymes is of fundamental importance for many biochemical processes. Enhanced or directed enzyme diffusion can alter the accessibility of substrates and the organization of enzymes within cells.
Fischer, Peer, Günther, Jan-Philipp, Majer, Günter   +2 more
core   +1 more source

Tolerance to Phosphorus Deficiency Improves Seed Phytic Acid‐to‐Iron Molar Ratios in Common Bean

Plant, Cell &Environment, EarlyView.
ABSTRACT Although significant advances have been achieved in the biofortification of common beans to overcome deficiencies in Zinc (Zn) and iron (Fe), the mechanisms involved remain poorly understood. We thus explored the relationships between phosphorus nutrition and Zn and Fe accumulation in four bean genotypes (Edar, Nizok, Colorado and Chimbolos ...
Barbara Karpinska, Christine H. Foyer
wiley   +1 more source

Nonconservative utilization of aldolase A alternative promoters.

Journal of Biological Chemistry, 1990
Recently, analysis of the sequence and expression of the human aldolase A gene revealed the unique arrangement of three tandem promoters and exons preceding a common coding sequence. A muscle-specific promoter (M) and two flanking widely used promoters (N and H) produce mRNA species which, in their mature forms, differ only in the sequence of their 5 ...
J K, Stauffer, M C, Colbert, E, Ciejek-Baez   +2 more
openaire   +2 more sources

Phosphate Resupply Differentially Impacts the Shoot and Root Proteomes of Arabidopsis thaliana Seedlings

Plant, Cell &Environment, EarlyView.
ABSTRACT Phosphate (Pi) is an essential macronutrient for plant development that is often limited in soil. Plants have evolved dynamic biochemical, physiological and morphological adaptations to cope with Pi deficiency, known as the Pi starvation response (PSR).
Milena A. Smith, Lauren E. Grubb, Kirsten H. Benidickson, Devang Mehta, William C. Plaxton, R. Glen Uhrig   +5 more
wiley   +1 more source

Irreversible inhibition of aldolase by a phosphorylated α-dicarbonyl compound

Journal of Enzyme Inhibition and Medicinal Chemistry, 2008
The preparation of a phosphorylated alpha-dicarbonyl compound designed to specifically react with arginine residues of enzymes accepting phosphorylated compounds as effectors is reported, and shown to inhibit rabbit muscle aldolase in a time-dependent and irreversible manner.
Chabot, Nicolas, Vinatier, Virginie, Gefflaut, Thierry, Baudoin-Dehoux, Cécile, Rodriguez, Frédéric, Blonski, Casimir, Hoffmann, Pascal   +6 more
openaire   +3 more sources

Longitudinal metabolomics study of phosphate‐adenine‐guanosine‐glucose‐saline‐mannitol stored red blood cells

Transfusion, EarlyView.
Abstract Background The storage of red blood cells (RBCs) is essential for transfusion but leads to storage lesions that compromise RBC quality and increase the risk of transfusion‐related adverse effects, including allergic transfusion reactions (ATRs). Understanding storage‐induced metabolic change is crucial for enhancing transfusion safety.
Gürkan Bal, Maia Dzamashvili, Zhuoran Li, Magda Babina, Nidal Toman, Abdulgabar Salama   +5 more
wiley   +1 more source

Integrated GWAS and Fst analysis identify flowering‐time regulatory genes in maize

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Flowering time in maize is a complex quantitative trait regulated by multiple genes, and its genetic variation mechanisms remain to be fully elucidated. In this study, we phenotypically evaluated flowering‐related traits (days to tasseling, days to pollen shedding, days to silking) across six different environments using an association ...
Dong Wang, Zhuoya Gao, Mengyue Dong, Tuan Li, Wenjing Zhou, Jialei Ou, Shiya Zhang, Shuaishuai Zhang, Xian Dong, Yalan Li, Caihui Zhang, Jiahao Tie, Yinuo Wang, Gaoyang Sun, Huiling Xie, Weihua Li, Jihua Tang, Pengshuai Yan   +17 more
wiley   +1 more source

Carboxyl‐Terminal Region of the Maturation Protein of RNA Coliphage Qβ Mediates Host Attachment, Virion Formation, and Cell Lysis

Genes to Cells, Volume 31, Issue 2, March 2026.
The capsid of the single‐stranded RNA coliphage Qβ has a maturation (A2) protein that penetrates the capsid. The N‐terminal β‐region of A2 is exposed on the surface, and the C‐terminal α‐region is located inside the capsid and binds the genomic RNA. In this study, we showed that Qβ attached to the F‐pilus of the host via A2.
Masayuki Kajitani, Noriko Hakoshima, Yoshio Inokuchi   +2 more
wiley   +1 more source

Epitope-Based Peptide Vaccine Against Fructose-Bisphosphate Aldolase of Using Immunoinformatics Approaches

Bioinformatics and Biology Insights, 2018
Background: Mycetoma is a distinct body tissue destructive and neglected tropical disease. It is endemic in many tropical and subtropical countries.
Arwa A Mohammed, Ayman MH ALnaby, Solima M Sabeel, Fagr M AbdElmarouf, Amina I Dirar, Mostafa M Ali, Mustafa A Khandgawi, Abdelhameed M Yousif, Eman M Abdulgadir, Magdi A Sabahalkhair, Ayman E Abbas, Mohammed A Hassan   +11 more
doaj   +1 more source